Classification and application of metal-based nanoantioxidants in medicine and healthcare.

Autor: Nam NN; Applied Biology Center, School of Agriculture and Aquaculture, Tra Vinh University, Tra Vinh City 87000, Vietnam., Tran NKS; College of Korean Medicine, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Republic of Korea., Nguyen TT; Department of Materials Science, School of Applied Chemistry, Tra Vinh University, Tra Vinh City 87000, Vietnam., Trai NN; Applied Biology Center, School of Agriculture and Aquaculture, Tra Vinh University, Tra Vinh City 87000, Vietnam., Thuy NP; Applied Biology Center, School of Agriculture and Aquaculture, Tra Vinh University, Tra Vinh City 87000, Vietnam., Do HDK; NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ward 13, District 04, Ho Chi Minh City 70000, Vietnam., Tran NHT; Faculty of Materials Science and Technology, University of Science, Ho Chi Minh City, Vietnam.; Vietnam National University Ho Chi Minh City, Vietnam., Trinh KTL; BioNano Applications Research Center, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 13120, Republic of Korea.
Jazyk: angličtina
Zdroj: Beilstein journal of nanotechnology [Beilstein J Nanotechnol] 2024 Apr 12; Vol. 15, pp. 396-415. Date of Electronic Publication: 2024 Apr 12 (Print Publication: 2024).
DOI: 10.3762/bjnano.15.36
Abstrakt: Antioxidants play an important role in the prevention of oxidative stress and have been widely used in medicine and healthcare. However, natural antioxidants have several limitations such as low stability, difficult long-term storage, and high cost of large-scale production. Along with significant advances in nanotechnology, nanomaterials have emerged as a promising solution to improve the limitations of natural antioxidants because of their high stability, easy storage, time effectiveness, and low cost. Among various types of nanomaterials exhibiting antioxidant activity, metal-based nanoantioxidants show excellent reactivity because of the presence of an unpaired electron in their atomic structure. In this review, we summarize some novel metal-based nanoantioxidants and classify them into two main categories, namely chain-breaking and preventive antioxidant nanomaterials. In addition, the applications of antioxidant nanomaterials in medicine and healthcare are also discussed. This review provides a deeper understanding of the mechanisms of metal-based nanoantioxidants and a guideline for using these nanomaterials in medicine and healthcare.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2024, Nam et al.)
Databáze: MEDLINE