The Impact of Vaccination Among Hospitalized Patients with the Diagnosis of COVID-19.

Autor:	Yıldız Y; Department of Infectious Disease and Clinical Microbiology, Gazi University School of Medicine, Ankara, Turkey., Özger HS; Department of Infectious Disease and Clinical Microbiology, Gazi University School of Medicine, Ankara, Turkey., Acar A; Department of Infectious Disease and Clinical Microbiology, Atılım University School of Medicine, Ankara, Turkey., Seremet-Keskin A; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Antalya Training and Research Hospital, Antalya, Turkey., Binay UD; Department of Infectious Diseases and Clinical Microbiology, Erzincan Binali Yildirim University School of Medicine, Erzincan, Turkey., Ünlü G; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey., Bayram H; Department of Infectious Diseases and Clinical Microbiology, Gaziantep Dr Ersin Arslan Tranining and Research Hospital, Gaziantep, Turkey., Asan A; Department of Infectious Diseases and Clinical Microbiology, University of Health Science, Bursa Training and Research Hospital, Bursa, Turkey., Akça MÖ; Department of Infectious Diseases and Clinical Microbiology, University of Health Science, Bursa Training and Research Hospital, Bursa, Turkey., Karamanlioğlu D; Department of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Ankara, Turkey., İnan O; Department of Internal Medicine, Ankara City Hospital, Ankara, Turkey., Kaya Ş; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences Diyarbakır Gazi Yasargil Training and Research Hospital, Diyarbakır, Turkey., Yıldırım Ç; Department of Infectious Diseases and Clinical Microbiology, Pursaklar State Hospital, Ankara, Turkey., Arslan Y; Department of Infectious Diseases and Clinical Microbiology, Batman Training and Research Hospital, Batman, Turkey., Kömür S; Department of Infectious Disease and Clinical Microbiology, Çukurova University School of Medicine, Adana, Turkey., Saygıdeğer Y; Department of Pulmonary, Çukurova University School of Medicine, Adana, Turkey., Kandemir FÖ; Department of Infectious Disease and Clinical Microbiology, Mersin University School of Medicine, Mersin, Turkey., Yaşar S; Department of Infectious Disease and Clinical Microbiology, Mersin University School of Medicine, Mersin, Turkey., Akdemir-Kalkan İ; Department of Infectious Diseases and Clinical Microbiology, Ankara University School of Medicine, Ankara, Turkey., Tekin-Taş Z; Department of Infectious Diseases and Clinical Microbiology, Sincan Dr. Nafiz Körez State Hospital, Ankara, Turkey., Sakız A; Department of Infectious Diseases and Clinical Microbiology, Mardin Training and Research Hospital, Mardin, Turkey., Bayındır Y; Department of Infectious Diseases and Clinical Microbiology, İnönü University School of Medicine, Malatya, Turkey., Özer AB; Department of Anesthesiology and Reanimation, İnönü University School of Medicine, Malatya, Turkey., Mete AÖ; Department of Infectious Diseases and Clinical Microbiology, Gaziantep University School of Medicine, Gaziantep, Turkey., Erol Ç; Department of Infectious Diseases and Clinical Microbiology, Başkent University School of Medicine, Ankara, Turkey., Mermutluoğlu Ç; Department of Infectious Diseases and Clinical Microbiology, Dicle University School of Medicine, Diyarbakir, Turkey., Kadiroğlu AK; Department of Nephrology, Dicle University School of Medicine, Diyarbakır, Turkey., Azap A; Department of Infectious Diseases and Clinical Microbiology, Ankara University School of Medicine, Ankara, Turkey., Şenol E; Department of Infectious Disease and Clinical Microbiology, Gazi University School of Medicine, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Infectious diseases & clinical microbiology [Infect Dis Clin Microbiol] 2023 Jun 23; Vol. 5 (2), pp. 118-126. Date of Electronic Publication: 2023 Jun 23 (Print Publication: 2023).
DOI:	10.36519/idcm.2023.216
Abstrakt:	Objective: We aimed to investigate the vaccination status and the risk factors for the intensive care unit (ICU) support need of the laboratory-confirmed breakthrough COVID-19 infection inpatients. Materials and Methods: This multi-center point-prevalence study was conducted on inpatients, divided into two groups as 'fully' and 'partially' vaccinated according to COVID-19 vaccination status. Results: Totally 516 patients were included in the study. The median age was 65 (55-77), and 53.5% (n=276) of the patients were male. Hypertension (41.9%, n=216), diabetes mellitus (DM) (31.8%, n=164), and coronary artery disease (CAD) (16.3%, n=84) were the predominant comorbidities. Patients were divided into two groups ICU (n=196) and non-ICU (n=301). Hypertension ( p =0.026), DM ( p =0.048), and congestive heart failure (CHF) ( p =0.005) were significantly higher in ICU patients and the median age was younger among non-ICU patients ( p =0.033). Of patients, 16.9% (n=87) were fully vaccinated, and this group's need for ICU support was statistically significantly lower ( p =0.021). Conclusion: We conclude that older age, hypertension, DM, CHF, and being partially vaccinated were associated with the need for ICU support. Therefore, all countries should continuously monitor post-vaccination breakthrough COVID-19 infections to determine the national booster vaccine administration approach that will provide vulnerable individuals the highest protection. Competing Interests: The authors declare no conflict of interest. (Copyright © 2024 Infectious Diseases and Clinical Microbiology.)
Databáze:	MEDLINE
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