A novel methionine nanoparticle in broiler chickens: Bioavailability and requirements.

Autor: Ghazaghi M; Department of Animal Sciences, Faculty of Agriculture, University of Zabol, Zabol, Sistan, IRAN., Mehri M; Department of Education, Shahid Motahari High School, Ministry of Education, Zahedan, IRAN., Asghari-Moghadam M; Department of Animal Sciences, Faculty of Agriculture, University of Zabol, Zabol, Sistan, IRAN., Mehri M; Department of Animal Sciences, Faculty of Agriculture, University of Zabol, Zabol, Sistan, IRAN.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Apr 17; Vol. 19 (4), pp. e0302230. Date of Electronic Publication: 2024 Apr 17 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0302230
Abstrakt: This bioassay evaluated the bioavailability (RBV) of a novel nanoparticle of methionine (nano-Met) relative to DL-methionine (DL-Met), and estimated methionine requirements for both sources in starting broilers. Five supplemental levels (0.05, 0.10, 0.15, 0.20, and 0.25% of diet) of DL-Met or nano-Met were added to a basal diet containing 0.35% standardized ileal digestible (SID) methionine to create 11 experimental diets, including a basal diet and 10 experimental diets containing 0.40, 0.45, 0.50, 0.55, and 0.60% SID-Met, respectively. A total of 825 one-day-old male Ross 308 birds were randomly assigned to 11 treatments with 5 pen replicates and 15 birds each. Body weight gain (BWG), breast meat yield (BMY), and thigh meat yield (TMY) increased (P < 0.001) while feed conversion ratio (FCR) and malondialdehyde (MDA) concentration in meat samples decreased (P < 0.001) with increasing dietary methionine. Based on the slope-ratio method, the RBV of nano-Met relative to DL-Met for BWG, FCR, and TMY were 102 (48-155%; R2 = 0.71), 134 (68-201%; R2 = 0.77), and 110% (27-193%; R2 = 0.55), respectively. Considering the statistical accuracy of the spline models, the estimated values of DL-Met for maximum BWG and nano-Met for maximum TMY were 0.578% and 0.561%, respectively, which were statistically higher than those recommended for commercial settings. The highest effect size of supplemental methionine was on MDA (ƞ2p = 0.924), followed by FCR (ƞ2p = 0.578), BMY (ƞ2p = 0.575), BWG (ƞ2p = 0.430), and TMY (ƞ2p = 0.332), suggesting the potent antioxidant properties of methionine. Our findings suggest that reducing the particle size of DL-Met to nanoparticles could be a promising strategy to enhance the efficiency of methionine supplementation in broilers, an idea that requires further investigation in future research.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Ghazaghi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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