Refraction and topographic risk factors for early myopic regression after small-incision lenticule extraction surgery.

Autor: Lee CY; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Nobel Eye Institute, No. 13-5, Gongyuan Rd., Zhongzheng Dist., Taipei, 100008, Taiwan.; Department of Ophthalmology, Jen-Ai Hospital Dali Branch, Taichung, Taiwan., Jeng YT; Nobel Eye Institute, No. 13-5, Gongyuan Rd., Zhongzheng Dist., Taipei, 100008, Taiwan., Chao CC; Nobel Eye Institute, No. 13-5, Gongyuan Rd., Zhongzheng Dist., Taipei, 100008, Taiwan.; Department of Optometry, MacKay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan., Lian IB; Institute of Statistical and Information Science, National Changhua University of Education, Changhua, Taiwan., Huang JY; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan. ysf@csmu.edu.tw.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan. ysf@csmu.edu.tw., Chang CK; Nobel Eye Institute, No. 13-5, Gongyuan Rd., Zhongzheng Dist., Taipei, 100008, Taiwan. chaokai@mail.dyu.edu.tw.; Department of Optometry, Da-Yeh University, Chunghua, Taiwan. chaokai@mail.dyu.edu.tw.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Apr 16; Vol. 14 (1), pp. 8732. Date of Electronic Publication: 2024 Apr 16.
DOI: 10.1038/s41598-024-59327-6
Abstrakt: We sought to evaluate the topographic risk factors for early myopic regression after small-incision lenticule extraction (SMILE). A retrospective case‒control study was conducted, and individuals who underwent SMILE surgery were enrolled. Among them, 406 and 14 eyes were categorized into the nonregression and regression groups, respectively. The preoperative and postoperative parameters in the two groups were collected, including spherical refraction (SE), axial length (AXL) and topographic data. A generalized linear model was adopted to analyze the difference in each parameter between the two groups. After 6 months, UCVA decreased in the regression group, and SE increased in the regression group (both P < 0.05). The increase in the CCT at the thinnest point (P = 0.044), flat corneal curvature (P = 0.012) and TCRP (P = 0.001) were significantly greater in the regression group. Regarding the risk factors for myopic regression, preoperative SE, preoperative sphere power, preoperative AXL, preoperative flat corneal curvature, preoperative SA, early postoperative SE, early postoperative sphere power, early postoperative AXL and early postoperative CCT difference were significantly greater in the regression group (all P < 0.05). The SE, sphere power, AXL, preoperative flat corneal curvature, preoperative SA, and postoperative CCT difference correlate with early myopic regression after SMILE.
(© 2024. The Author(s).)
Databáze: MEDLINE
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