Cornual adenomyosis in Essure® device users and in patients hysterectomized for other causes: A retrospective cohort study.

Autor: Sánchez-Cuerda C; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., Elices M; Department of Anatomy Pathology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain., Lobo P; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., Cabrera Y; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., Duch S; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., García A; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain., Rubio J; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., Álvarez J; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain., Álvarez P; Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.; European University Madrid, Villaviciosa de Odón, Madrid, Spain.
Jazyk: angličtina
Zdroj: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2024 Oct; Vol. 167 (1), pp. 185-190. Date of Electronic Publication: 2024 Apr 16.
DOI: 10.1002/ijgo.15541
Abstrakt: Objective: To determine whether adenomyosis is present in the cornual portion of hysterectomies of symptomatic sterilization device users and in patients hysterectomized for different benign causes and who presented with pelvic pain and/or menstrual alterations.
Methods: An observational, analytical, cross-sectional, single-center, retrospective cohort study was conducted in a secondary level hospital. Cohort 1 consisted of women who had Essure® hysteroscopic sterilization devices inserted between 2009 and 2017, who developed gynecologic symptoms (pelvic pain, heavy menstrual bleeding, and/or abnormal uterine bleeding) and who underwent a hysterectomy for explantation of the devices. Cohort 2 consisted of women with the same gynecologic symptoms, who underwent a hysterectomy for other benign causes. All surgeries were performed by the gynecology team between 2018 and 2022. A descriptive and comparative analysis of sociodemographic, clinical characteristics, and pathologic findings between cohorts was made.
Results: In total, 96 patients were studied (cohort 1 included 34 women, cohort 2 included 62 women). Pelvic pain was found to be more frequent in the cohort of Essure users (76.47% vs. 50%, P = 0.012), with a ratio of three times higher in this group (odds ratio 3.25, 95% confidence interval 1.27-8.28). Adenomyosis was more frequently found in the Essure group, both at corporal and cornual portions, the latter being five times higher in this cohort (relative risk = 5.47; 95% confidence interval 1.17-25.64).
Conclusions: The present study may be the first to describe cornual adenomyosis related to Essure devices. These devices may play a role in the development of adenomyosis and, consequently, pelvic pain. However, causality is difficult to establish.
(© 2024 International Federation of Gynecology and Obstetrics.)
Databáze: MEDLINE
Externí odkaz: