Tremorgenic mycotoxicosis in cattle, caused by  Claviceps paspali .

Autor: Ayala-Soldado N; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain., Lora-Benitez AJ; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain., Mora-Medina R; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain., Molina-Lopez AM; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain., Artillo-Guimera JI; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain., Moyano-Salvago MR; Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, Spain.
Jazyk: angličtina
Zdroj: Veterinarni medicina [Vet Med (Praha)] 2022 Sep 07; Vol. 67 (12), pp. 638-643. Date of Electronic Publication: 2022 Sep 07 (Print Publication: 2022).
DOI: 10.17221/25/2022-VETMED
Abstrakt: Claviceps paspali is a fungus that mainly parasitises Paspalum dilatatum , generating a structure denominated sclerotium, in which indole-diterpenoid alkaloids are isolated. Its action mechanism is related to the inhibition of the gamma-aminobutyric acid receptor. It basically affects bovines, triggering the tremorgenic syndrome, the prevalence of this intoxication being relatively low in Europe. This work describes a clinical case on a cattle farm in Seville (southern Spain), composed of 91 bovines, 60% of which were principally affected with nervous clinical signs. The diagnosis was based on a clinical inspection of the animals, as well as of the presence of paspalum seed heads containing the sclerotia of  Claviceps paspali in the plants present in the pastures. The causal agent was identified as being Claviceps paspali , which had parasitised numerous examples of  Paspalum paspaloides . The indole-diterpenoid alkaloids produced by  Claviceps paspali were identified using ultraviolet-visible spectrophotometry and mass spectrometry. At present, no effective aetiological treatment has been described for poisoning caused by this mycotoxin, so a supportive treatment was administered, and different handling methods were applied, resulting in the complete recovery of the animals. Finally, it was concluded that unusually high humidity and temperature levels for the region triggered the development of the sclerotium generated by this fungus.
Competing Interests: The authors declare no conflict of interest.
(Copyright: © 2022 Ayala-Soldado et al.)
Databáze: MEDLINE
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