Giant Cell Tumor in Tarsal Midfoot Bones: A Case Report.

Autor: Abed Alharbi W; Department of Orthopedics, King Fahad Armed Forces Hospital, Jeddah, SAU., Mohammed Alshareef H; Department of Orthopedic Surgery, King Fahad Armed Forces Hospital, Jeddah, SAU., Hennawi YB; College of Medicine, Umm Al-Qura University, Makkah, SAU., Munshi AA; College of Medicine, Umm Al-Qura University, Makkah, SAU., Khalid Alzahrani A; Department of Orthopedics, King Fahad Armed Forces Hospital, Jeddah, SAU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Mar 15; Vol. 16 (3), pp. e56215. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
DOI: 10.7759/cureus.56215
Abstrakt: Diffuse tenosynovial giant cell tumor (D-TGCT), previously known as pigmented villonodular synovitis (PVNS), is a benign, aggressive, and distracting proliferative synovial lesion. D-TGCT is commonly seen in large joints such as the knee and hip. We present the case of a 57-year-old female who initially presented with swelling on the left midfoot that increased over four years. Clinically, a ganglion was suspected on the left midfoot and an MRI showed a heterogeneous lobulated soft tissue mass on the superior aspect of the tarsal midfoot measuring 5.8 x 2.4 x 4.2 cm. The mass causing remodeling and bony erosion was more appreciated at the medial aspect of the talus bone and extended to the sinus tarsi and talocalcaneal joint space. Surgical excision of the mass was performed, and pathology reports found lobulated soft tissue lesions composed of mononuclear cells, multinucleated giant cells, sheets of foamy macrophages, inflammatory cells, and hemosiderin-laden macrophages. This case represents D-TGCT without atypia or malignancy based on the findings.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Abed Alharbi et al.)
Databáze: MEDLINE