Decoupling cell size homeostasis in diatoms from the geometrical constraints of the silica cell wall.

Autor: de Haan D; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel., Ramos NH; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel., Meng YF; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel., Rotkopf R; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 7610001, Israel., Addadi Y; Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 7610001, Israel., Rosenhek-Goldian I; Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, 7610001, Israel., Gal A; Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Jazyk: angličtina
Zdroj: The New phytologist [New Phytol] 2024 Jul; Vol. 243 (1), pp. 258-270. Date of Electronic Publication: 2024 Apr 15.
DOI: 10.1111/nph.19743
Abstrakt: Unicellular organisms are known to exert tight control over their cell size. In the case of diatoms, abundant eukaryotic microalgae, two opposing notions are widely accepted. On the one hand, the rigid silica cell wall that forms inside the parental cell is thought to enforce geometrical reduction of the cell size. On the other hand, numerous exceptions cast doubt on the generality of this model. Here, we monitored clonal cultures of the diatom Stephanopyxis turris for up to 2 yr, recording the sizes of thousands of cells, in order to follow the distribution of cell sizes in the population. Our results show that S. turris cultures above a certain size threshold undergo a gradual size reduction, in accordance with the postulated geometrical driving force. However, once the cell size reaches a lower threshold, it fluctuates around a constant size using the inherent elasticity of cell wall elements. These results reconcile the disparate observations on cell size regulation in diatoms by showing two distinct behaviors, reduction and homeostasis. The geometrical size reduction is the dominant driving force for large cells, but smaller cells have the flexibility to re-adjust the size of their new cell walls.
(© 2024 The Authors. New Phytologist © 2024 New Phytologist Foundation.)
Databáze: MEDLINE
Externí odkaz: