Role of micro-RNAs associated with adipose-derived extracellular vesicles in metabolic disorders.

Autor: Payet T; Aix Marseille Université, C2VN, INRAE, INSERM, Marseille, France., Gabinaud E; Aix Marseille Université, C2VN, INRAE, INSERM, Marseille, France., Landrier JF; Aix Marseille Université, C2VN, INRAE, INSERM, Marseille, France.; PhenoMARS Aix-Marseille Technology Platform, CriBiom, Marseille, France., Mounien L; Aix Marseille Université, C2VN, INRAE, INSERM, Marseille, France.; PhenoMARS Aix-Marseille Technology Platform, CriBiom, Marseille, France.
Jazyk: angličtina
Zdroj: Obesity reviews : an official journal of the International Association for the Study of Obesity [Obes Rev] 2024 Jul; Vol. 25 (7), pp. e13755. Date of Electronic Publication: 2024 Apr 15.
DOI: 10.1111/obr.13755
Abstrakt: Micro-RNAs have emerged as important actors in the onset of metabolic disorders including obesity or type 2 diabetes. Particularly, several micro-RNAs are known to be key modulators of lipid metabolism, glucose homeostasis, or feeding behavior. Interestingly, the role of extracellular vesicles containing micro-RNAs, especially adipose-derived extracellular vesicles, are well-documented endocrine signals and disease biomarkers. However, the role of adipose-derived extracellular vesicles on the different tissues is different and highly related to the micro-RNA content. This review provides recent data about the potential involvement of adipose-derived extracellular vesicle-containing micro-RNAs in metabolic diseases.
(© 2024 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.)
Databáze: MEDLINE
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