[Olfactory dysfunction in COVID-19, a review of the evidence and implications for pandemic management].

Autor:	Lop Gros J; Servicio de Anatomía Patológica, Hospital del Mar, Parc de Salut Mar, Barcelona, España., Iglesias Coma M; Servicio de Anatomía Patológica, Hospital del Mar, Parc de Salut Mar, Barcelona, España., González Farré M; Servicio de Anatomía Patológica, Hospital del Mar, Parc de Salut Mar, Barcelona, España., Serra Pujadas C; Servicio de Medicina Laboral, Hospital del Mar, Parc de Salut Mar, Barcelona, España.
Jazyk:	Spanish; Castilian
Zdroj:	Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp] 2020 Nov-Dec; Vol. 71 (6), pp. 379-385. Date of Electronic Publication: 2020 May 11.
DOI:	10.1016/j.otorri.2020.04.003
Abstrakt:	There is debate as to whether olfactory dysfunction should be considered a symptom of COVID-19 infection. We undertook a systematic literature review of the articles indexed in PubMed on olfactory disorders in viral respiratory tract conditions, with special emphasis on COVID-19. The main objective was to find evidence of clinical interest to support the relationship between anosmia and COVID-19. Olfactory disorders in upper respiratory tract infections are frequent, most caused by obstruction due to oedema of the nasal mucosa. Occasionally, post-viral sensorineural olfactory dysfunction occurs, with a variable prognosis. The evidence on anosmia in COVID-19 patients is extremely limited, corresponding to a level 5 or D of the Centre for Evidence-Based Medicine. According to the available evidence, it seems reasonable to apply isolation, hygiene and social distancing measures in patients with recent olfactory disorders as the only symptom, although the usefulness of diagnostic tests for this type of patient should be studied. (© 2020 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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