| Autor: |
Zhou HJ; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Yang MY; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Chen J; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Ji W; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Shao JH; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Wang ZH; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China., Zhao CC; Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou, China. |
| Abstrakt: |
This paper reports the isolation of two undescribed phenolic glycosides ( 1 and 2 ), together with seven known compounds ( 3 - 9 ) from the branches of Viburnum chinshanense . The structures of undescribed compounds were elucidated by comprehensive spectroscopic methods (1D NMR, 2D NMR, and HRESIMS). The sugar units of compounds 1 and 2 were identified by acid hydrolysis and HPLC analysis of the chiral derivatives of the monosaccharides. Furthermore, the α ‑amylase and α -glucosidase inhibitory activities of all isolates were evaluated and compounds 1 , 5 , and 8 displayed potential α ‑amylase and α -glucosidase inhibitory activities. The molecular docking analyses of compounds 1 and 8 with the potent inhibition towards the target enzymes were also performed. |
