Navigating the Uncharted Territory of Pediatric-Onset Multiple Sclerosis in a 12-Year-Old Male: A Case Study.
| Autor: | Grezenko H; Translational Neuroscience, Barrow Neurological Institute, Phoenix, USA., Shah IA; Internal Medicine, Chandka Medical College, Larkana, PAK., Sariza AA; Internal Medicine, Sriwijaya University, Palembang, IDN., Baluch AB; Internal Medicine, Universidad Autónoma de Guadalajara, Guadalajara, MEX., Kumar A; Internal Medicine, Civil Hospital Karachi, Karachi, PAK., Abubakar M; Internal Medicine, Wah Medical College, Wah Cantt, PAK. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Mar 14; Vol. 16 (3), pp. e56172. Date of Electronic Publication: 2024 Mar 14 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.56172 |
| Abstrakt: | This case report presents an atypical instance of pediatric-onset multiple sclerosis (MS) in a 12-year-old male, a demographic less commonly affected by this condition. The patient's clinical course was marked by severe and progressive symptoms, including lower limb weakness and loss of bowel/bladder control, diverging from the typical relapsing-remitting pattern observed in pediatric MS. Despite initial resistance to high-dose steroid treatment, his condition was ultimately stabilized through plasmapheresis, following the detection of myelin oligodendrocyte glycoprotein antibodies. Unique aspects of this case included the patient's young age, male gender, and the occurrence of osteopenia, as identified by a dual-energy X-ray absorptiometry scan. This report highlights the variability in MS presentations among pediatric patients and underscores the importance of a personalized, multidisciplinary approach to diagnosis and treatment. It contributes to the growing body of knowledge on pediatric MS, emphasizing the need for heightened clinical vigilance and tailored management strategies in young patients with this complex and lifelong disease. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Grezenko et al.) |
| Databáze: | MEDLINE |
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