Antioxidant and Anti-inflammatory Applications of Aerva persica Aqueous-Root Extract-Mediated Synthesis of ZnO Nanoparticles.

Autor:	Fatima K; Faculty of Pharmacy, Maulana Azad University, Bujhawad, Teh: Luni, Jodhpur 342802, Rajasthan, India.; INTI International University, Persiaran Perdana BBN, Putra Nilai, 71800 Nilai, Negeri Sembilan, Malaysia., Asif M; Faculty of Pharmacy, Lachoo Memorial College of Science and Technology, Shastri Nagar, Sector A, Jodhpur 342001, Rajasthan, India., Farooq U; Chemistry Department, School of Basic Sciences, Galgotias University, Greater Noida 201309, India., Gilani SJ; Department of Basic Health Sciences, Foundation Year, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia., Bin Jumah MN; Saudi Society for Applied Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.; Environment and Biomaterial Unit, Health Sciences Research Center, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.; Biology Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia., Ahmed MM; Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	ACS omega [ACS Omega] 2024 Mar 29; Vol. 9 (14), pp. 15882-15892. Date of Electronic Publication: 2024 Mar 29 (Print Publication: 2024).
DOI:	10.1021/acsomega.3c08143
Abstrakt:	In the present study, ZnO nanoparticles were synthesized by using aqueous extracts of Aerva persica roots. Characterization of as-prepared ZnO nanoparticles was carried out using different techniques, including powder X-ray diffraction (XRD), UV-vis diffuse reflectance spectroscopy (DRS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) and BET surface area analysis. Morphological analysis confirmed the small, aggregated flake-shaped morphology of as-synthesized ZnO nanostructures. The as-prepared ZnO nanoparticles were analyzed for their potential application as anti-inflammatory (using in vivo inhibition of carrageenan induced paw edema) and antioxidant (using in vitro radical scavenging activity) agents. The ZnO nanoparticles were found to have a potent antioxidant and anti-inflammatory activity comparable to that of standard ascorbic acid (antioxidant) and indomethacin (anti-inflammatory drug). Therefore, due to their ecofriendly synthesis, nontoxicity, and biocompatible nature, zinc oxide nanoparticles synthesized successfully from roots extract of the plant Aerva persica with potent efficiencies can be utilized for different biomedical applications. Competing Interests: The authors declare no competing financial interest. (© 2024 The Authors. Published by American Chemical Society.)
Databáze:	MEDLINE
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