Concurrent myocardial infarction in the setting of thrombotic thrombocytopenic purpura secondary to systemic lupus erythematosus: A case report.

Autor: Azadbakht S; Department of Internal Medicine, School of Medicine Lorestan University of Medical Sciences Khorramabad Iran., Amidi B; Department of Internal Medicine, School of Medicine Lorestan University of Medical Sciences Khorramabad Iran.; Student Research Committee Lorestan University of Medical Sciences Khorramabad Iran., Naderi N; Department of Internal Medicine, School of Medicine Lorestan University of Medical Sciences Khorramabad Iran.; Student Research Committee Lorestan University of Medical Sciences Khorramabad Iran., Sharifaskari A; Department of Internal Medicine, School of Medicine Lorestan University of Medical Sciences Khorramabad Iran., Hatami M; Department of Internal Medicine, School of Medicine Lorestan University of Medical Sciences Khorramabad Iran.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2024 Apr 11; Vol. 12 (4), pp. e8751. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
DOI: 10.1002/ccr3.8751
Abstrakt: Key Clinical Message: In acute thrombotic thrombocytopenic purpura (TTP), apart from urgent treatment, assessing the patient's medical history, especially conditions like systemic lupus erythematosus that could trigger TTP, is crucial. Rarely, TTP patients may experience cardiac conditions as severe as a myocardial infarction.
Abstract: A 45-year-old woman manifested severe and acute thrombotic thrombocytopenic purpura (TTP) of unknown origin. The patient's symptoms, the laboratory data, the detection of the reduction in ADAMTS13 activity, and the presence of schistocytes on the peripheral smear confirmed the diagnosis. The patient was then planned for therapeutic plasma exchange (TPE). Prior to the scheduled TPE, she suddenly experienced extreme shortness of breath and chest pain. An electrocardiogram was obtained immediately after reporting signs of an inferior myocardial infarction. Further examinations to acquire information about the patient's underlying medical conditions in order to study the secondary causes of TTP, combined with the results of the laboratory tests, resulted in the patient being diagnosed with systemic lupus erythematosus.
Competing Interests: The authors declare that there is no conflict of interest.
(© 2024 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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