The use of natural extracts with photoprotective activity: a 2015-2023 patent prospection.

Autor: Oliveira AMS; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil. ana_prin6@academico.ufs.br., de Souza Batista D; Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil., de Castro TN; Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil., Alves IA; Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil.; Department of Medicines, Faculty of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil., Souto RB; Department of Medicines, Faculty of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil., Mota MD; Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil., Serafini MR; Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil., Rajkumar G; Department of Botany, Sri Sarada College for Women (Autonomous), Periyar University, Salem, India., Cazedey ECL; Postgraduate Program in Pharmaceutical Sciences, Department of Life Sciences, State University of Bahia, Salvador, Bahia, Brazil.; Department of Medicines, Faculty of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil.
Jazyk: angličtina
Zdroj: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology [Photochem Photobiol Sci] 2024 May; Vol. 23 (5), pp. 853-869. Date of Electronic Publication: 2024 Apr 13.
DOI: 10.1007/s43630-024-00559-w
Abstrakt: Synthetic sunscreen offers protection against excessive exposure to ultraviolet (UV) radiation from the sun, and protects the skin from possible damage. However, they have low efficacy against the formation of reactive oxygen species (ROS), which are highly reactive molecules that can be generated in the skin when it is exposed to UV radiation, and are known to play a role in oxidative stress, which can contribute to skin aging and damage. Thus, there is an ongoing search for sunscreens that do not have these negative effects. One promising source for these is natural products. Therefore, the current patent review summarizes topical formulations made from natural compounds that have antioxidant properties and can be used as photoprotective or anti-aging agents, either using a single natural extract or a combination of extracts. The review reports basic patent information (applicant country, type of applicant, and year of filing) and gives details about the invention, including its chemical composition, and the in vitro and in vivo tests performed. These patents describe natural products that can be used to protect the skin and validate their efficacy, and safety, in addition to standardizing their formulations. The compositions described illustrate the consistent innovation in the use of natural products to protect against UV damage and photoaging disorders, a promising field which is receiving growing global recognition.
(© 2024. The Author(s), under exclusive licence to the European Photochemistry Association, European Society for Photobiology.)
Databáze: MEDLINE
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