Long-term Changes in Personal Recovery and Quality of Life Among Patients With Schizophrenia Spectrum Disorders and Different Durations of Illness: A Meta-analysis.

Autor: de Winter L; Phrenos Center of Expertise, Utrecht, the Netherlands.; Department of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands., Jelsma A; Department of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands., Vermeulen JM; Department of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands., van Weeghel J; Tranzo, Tilburg University, Tilburg, the Netherlands., Hasson-Ohayon I; Department of Psychology, Bar-Ilan University, Ramat-Gan, Israel., Mulder CL; Epidemiological and Social Psychiatric Research Institute, Erasmus Medical Center,  Rotterdam, the Netherlands.; Parnassia Psychiatric Institute, Rotterdam, the Netherlands., Boonstra N; NHL Stenden University of Applied Science, Leeuwarden, the Netherlands.; University Medical Center Utrecht, Division Neuroscience, Utrecht, the Netherlands., Veling W; University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Haan L; Department of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands.
Jazyk: angličtina
Zdroj: Schizophrenia bulletin [Schizophr Bull] 2024 Apr 13. Date of Electronic Publication: 2024 Apr 13.
DOI: 10.1093/schbul/sbae045
Abstrakt: Background and Hypothesis: In schizophrenia spectrum disorders (SSD) personal recovery and subjective quality of life (S-QOL) are crucial and show conceptual overlap. There is limited knowledge about how these outcomes change over time. Therefore, we investigated changes in personal recovery or S-QOL for patients with SSD. We specifically focused on the influence of the patients' durations of illness (DOI) on changes in personal recovery and S-QOL.
Study Design: We included 46 studies investigating longitudinal changes in quantitative assessments of personal recovery or S-QOL for patients with SSD. Outcomes were categorized in overall personal recovery, overall S-QOL connectedness, hope and optimism, identity, meaning in life, and empowerment. We evaluated effect sizes of change between baseline and follow-up assessments. We also evaluated potential moderating effects, including DOI on these changes in outcomes.
Study Results: We found small improvements of overall personal recovery and S-QOL, but marginal or no improvement over time in the other more specific outcome domains. Patients without a schizophrenia diagnosis, a younger age, and more recent publications positively influenced these changes. We found no significant influence of DOI on the changes in any outcome domain.
Conclusions: Improvement in personal recovery or S-QOL of people with SSD is modest at best. However, these studies did not fully capture the personal narratives or nonlinear process of recovery of an individual. Future research should focus on how to shift from a clinical to more person-oriented approach in clinical practice to support patients in improving their personal process of recovery.
Review Protocol Registration: CRD42022377100.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.)
Databáze: MEDLINE