| Autor: |
Song Y; Department of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore., Lee SY; Division of Gastroenterology & Hepatology, Department of Medicine, National University Hospital, Singapore 119074, Singapore., Chee YL; Department of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore., Jen WY; Department of Haematology-Oncology, National University Cancer Institute, Singapore 119074, Singapore. |
| Abstrakt: |
Thrombotic microangiopathy (TMA) is associated with both hypertensive emergency and primary thrombocytopenia purpura (TTP). However, their clinical management is vastly different, with the latter necessitating urgent plasma exchange (PEX). We report two cases of hypertension-associated TMA (HTN-TMA) and a literature review of the clinical management of malignant hypertension. We suggest that in patients presenting with hypertensive emergency associated with TMA, a clinical diagnosis of HTN-TMA should be made, with emergent treatment to lower blood pressure started immediately. Although TTP is a differential diagnosis for TMA, PEX should not be started concurrently in the absence of other supporting evidence for TTP. |
