Network analysis on psychopathological symptoms, psychological measures, quality of life and COVID-19 related factors in Chinese psychiatric patients in Hong Kong.

Autor: Fung VSC; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chan JKN; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chui EMC; Department of Psychiatry, Queen Mary Hospital, Hospital Authority, Kowloon, Hong Kong., Wong CSM; School of Public Health, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chu RST; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., So YK; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chan JMT; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chung AKK; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Lee KCK; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Lo HKY; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Cheng CPW; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Law CW; Department of Psychiatry, Queen Mary Hospital, Hospital Authority, Kowloon, Hong Kong., Chan WC; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong., Chang WC; Department of Psychiatry, School of Clinical medicine, LKS Faculty of Medicine, the University of Hong Kong, Pok Fu Lam, Hong Kong. changwc@hku.hk.; State Key Laboratory of Brain and Cognitive Science, the University of Hong Kong, Pok Fu Lam, Hong Kong. changwc@hku.hk.; Department of Psychiatry, The University of Hong Kong Queen Mary Hospital, Pokfulam, Hong Kong. changwc@hku.hk.
Jazyk: angličtina
Zdroj: BMC psychiatry [BMC Psychiatry] 2024 Apr 12; Vol. 24 (1), pp. 271. Date of Electronic Publication: 2024 Apr 12.
DOI: 10.1186/s12888-024-05690-7
Abstrakt: Background: Psychiatric patients are susceptible to adverse mental health impacts during COVID-19, but complex interplays between psychopathology and pandemic-related variables remain elusive. This study aimed to investigate concomitant associations between psychopathological symptoms, psychological measures and COVID-19 related variables in Chinese psychiatric patients during the peak of fifth pandemic wave in Hong Kong.
Methods: We employed network analysis to investigate inter-relationships among psychopathological symptoms (including depression, anxiety, post-traumatic stress disorder-like [PTSD-like] symptoms, insomnia, psychotic symptoms), cognitive complaints, health-related quality of life, loneliness, resilience and selected pandemic-related factors in 415 psychiatric outpatients between 28 March and 8 April, 2022. Network comparisons between genders, diagnosis (common mental disorders [CMD] vs. severe mental disorders [SMD]), and history of contracting COVID-19 at fifth wave were performed as exploratory analyses.
Results: Our results showed that anxiety represented the most central node in the network, as indicated by its highest node strength and expected influence, followed by depression and quality of life. Three comparatively strong connections between COVID-19 and psychopathological variables were observed including: fear of contagion and PTSD-like symptoms, COVID-19 stressor burden and PTSD-like symptoms, and COVID-19 stressor burden and insomnia. Network comparison tests revealed significant network structural difference between participants with history of contracting COVID-19 and those without, but showed no significant difference between genders as well as between CMD and SMD patients.
Conclusions: Our findings suggest the pivotal role of anxiety in psychopathology network of psychiatric patients amidst COVID-19. Pandemic-related variables are critically associated with trauma/stress and insomnia symptoms. Future research is required to elucidate potential network structural changes between pandemic and post-COVID periods.
(© 2024. The Author(s).)
Databáze: MEDLINE
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