Evaluation of isotretinoin effects on depression, sleep apnea and sleep quality.
| Autor: | Orenay OM; Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey., Temel B; Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey., Capci AK; Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey., Bal ZI; Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey., Karaosmanoglu N; Department of Dermatology, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Cutaneous and ocular toxicology [Cutan Ocul Toxicol] 2024 Jun; Vol. 43 (2), pp. 129-133. Date of Electronic Publication: 2024 Apr 17. |
| DOI: | 10.1080/15569527.2024.2340435 |
| Abstrakt: | Background: Isotretinoin is used to treat severe acne, treatment-resistant moderate acne, and acne that leads to scarring or psychological distress. It has many side effects and is also associated with depression, sleep apnea, and sleep disturbances. Objectives: In this study, we aimed to evaluate the effects of isotretinoin on depression, sleep apnea, and sleep quality. Methods: A total of 42 patients diagnosed with acne and started isotretinoin treatment were included in the study. In order to compare the effects of isotretinoin, patients were asked to fill out a questionnaire containing the Beck Depression Inventory (BDI), the Berlin Questionnaire (BQ), and the Pittsburg Sleep Quality Index (PSQI) at baseline and third months of treatment. Results: There was no statistically significant difference in BDI, BQ, and PSQI scores between the 1 st and 3 rd months of treatment ( p = .53, p = .5, p = .35). Conclusion: This study showed that isotretinoin had no significant effects on depression and sleep quality. |
| Databáze: | MEDLINE |
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