Lymphovascular Invasion in Cutaneous Squamous Cell Carcinoma.
| Autor: | Ryan MP; Department of Dermatology, University of Texas Health Science Center at Houston, Houston, Texas., Winsett FT; Department of Dermatology, University of Texas Medical Branch, Galveston, Texas., Armenta AM; Department of Dermatology, University of Texas Medical Branch, Galveston, Texas., Goodwin BP; Department of Dermatology, University of Texas Medical Branch, Galveston, Texas., Wagner RF Jr; Department of Dermatology, University of Texas Medical Branch, Galveston, Texas. |
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| Jazyk: | angličtina |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2024 Aug 01; Vol. 50 (8), pp. 699-704. Date of Electronic Publication: 2024 Apr 10. |
| DOI: | 10.1097/DSS.0000000000004187 |
| Abstrakt: | Background: Although there is a large body of literature regarding risk stratification and outcomes for perineural invasion (PNI) in cutaneous squamous cell carcinoma (cSCC), there is a relative paucity of studies exploring the role of lymphovascular invasion (LVI) in cSCC and a lack of clear evidence-based guidelines for how to manage patients with these tumors. Objective: This article is intended to review the available literature regarding LVI in cSCC and formulate evidence-based recommendations for clinical management. Methods and Materials: A literature review was conducted using PubMed to find relevant articles relating to outcomes and management of primary cSCC with LVI. Results: The available literature suggests that LVI is a major risk factor for poor outcomes and increased morbidity and mortality in cSCC. Conclusion: Lymphovascular invasion is a very high-risk feature that should place these tumors in the highest-risk category, and management of these tumors should be similar to that of squamous cell carcinoma with PNI. (Copyright © 2024 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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