Colonic adenomatous polyp with florid presence of monoclonal lambda Russell bodies: Case report and etiopathogenic hypothesis.
| Autor: | Martínez-Aracil A; Pathology Service, Bioaraba Research Health Institute, Araba University Hospital, Vitoria-Gasteiz, Alava, Spain., Polanco-Alonso D; Molecular (Epi)Genetic Lab, Bioaraba Research Health Institute, Araba University Hospital, Vitoria-Gasteiz, Alava, Spain., Stayerman C; Laboratorio Technipath-Hospital del Valle, San Pedro Sula, Honduras., Miguel C; Pathology Service, Bioaraba Research Health Institute, Araba University Hospital, Vitoria-Gasteiz, Alava, Spain., Pérez de Nanclares G; Molecular (Epi)Genetic Lab, Bioaraba Research Health Institute, Araba University Hospital, Vitoria-Gasteiz, Alava, Spain. Electronic address: gnanclares@osakidetza.eus. |
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| Jazyk: | angličtina |
| Zdroj: | Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia [Rev Esp Patol] 2024 Apr-Jun; Vol. 57 (2), pp. 111-115. Date of Electronic Publication: 2023 Sep 04. |
| DOI: | 10.1016/j.patol.2023.07.001 |
| Abstrakt: | Russell bodies (RBs) are round eosinophilic intracytoplasmic inclusions formed by condensed immunoglobulins in mature plasma cells, which are called Mott cells. These cells are rarely found in the gastric tract, with even less cases reported in the colorectal region. There are still many questions about this event, as it is still unknown the relationship between the agents reported of increasing the probability of appearance of these cells and the generation of RBs. In this case report we describe the fifth patient presenting an infiltration of Mott cells in a colorectal polyp, being the second case with a monoclonal origin without a neoplastic cause, and the first one monoclonal for lambda. A comparison with previously similar reported cases is also done, and a possible etiopathogenic hypothesis proposed. (Copyright © 2023 Sociedad Española de Anatomía Patológica. Publicado por Elsevier España, S.L.U. All rights reserved.) |
| Databáze: | MEDLINE |
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