Gums make IL-23, no professionals needed.
| Autor: | McGeachy MJ; Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca NY 14853, USA. Electronic address: mandymcgeachy@cornell.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Immunity [Immunity] 2024 Apr 09; Vol. 57 (4), pp. 832-834. |
| DOI: | 10.1016/j.immuni.2024.03.009 |
| Abstrakt: | IL-23 activates pathogenic Th17 cells to drive inflammatory disease at barrier surfaces. Kim et al. now identify oral epithelial cells as the critical producers of IL-23 in human and mouse periodontitis, linking microbial dysbiosis to non-hematopoietic regulation of IL-17-associated inflammation. Competing Interests: Declaration of interests The author declares no competing interests. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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