Redox profile of silver catfish challenged with Aeromonas hydrophila and treated with hexane extract of Hesperozygis ringens (Benth.) Epling through immersion bath.

Autor:	Rosa IA; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Bianchini AE; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Bressan CA; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Ferrari FT; Universidade Federal de Santa Maria, Curso de Farmácia, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Ariotti K; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Mori NC; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.; Universidade de Cruz Alta (UNICRUZ), Curso de Farmácia, Rodovia Municipal Jacob Della Mea, s/n, km 5,6, 98020-290 Cruz Alta, RS, Brazil., Bandeira Junior G; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Pinheiro CG; Programa de Pós-Graduação em Engenharia Florestal, Universidade Federal de Santa Maria, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Pavanato MA; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.; Universidade Federal de Santa Maria, Departamento de Fisiologia e Farmacologia, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Cargnelutti JF; Universidade Federal de Santa Maria, Departamento de Medicina Veterinária Preventiva, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Baldisserotto B; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.; Universidade Federal de Santa Maria, Departamento de Fisiologia e Farmacologia, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil., Heinzmann BM; Programa de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.; Universidade Federal de Santa Maria, Curso de Farmácia, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.; Universidade Federal de Santa Maria, Departamento de Farmácia Industrial, Av. Roraima, 1000, 97105-900 Santa Maria, RS, Brazil.
Jazyk:	angličtina
Zdroj:	Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2024 Apr 05; Vol. 96 (1), pp. e20230188. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).
DOI:	10.1590/0001-3765202420230188
Abstrakt:	The growing increase in the fish farming sector has favored the establishment of bacterial outbreaks caused by Aeromonas hydrophila in several species. The hexane extract of Hesperozygis ringens (HEHR) (Lamiaceae) leaves increased the survival rate of silver catfish (Rhamdia quelen) experimentally infected by A. hydrophila. However, it is noteworthy that no reports have been found on the possible mechanisms of action of this extract in infected fish. This study aimed to evaluate the effect of the HEHR, administered through single immersion bath, on lipid peroxidation and antioxidant defenses in muscle and liver tissue of silver catfish challenged with A. hydrophila. The results showed that the oxidative status of silver catfish was altered, although oxidative stress was not triggered during the experiment. HEHR at 30 mg/L (HEHR30) was not characterized as a pro-oxidant agent in the presence of infection, unlike florfenicol and HEHR at 15 mg/L treatments in some cases. In short, HEHR30 provided an important increase in hepatic catalase activity, characterizing one of the possible mechanisms involved in the greater survival of fish experimentally infected by A. hydrophila. Additionally, HEHR30 did not induce lipid peroxidation, nor reduced antioxidant defenses of silver catfish infected or not by A. hydrophila.
Databáze:	MEDLINE
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