A Preclinical Blinded Randomized-Controlled Trial Evaluating the Clinical Relevance of Polyp Size Measurement Using a Virtual Scale Endoscope.

Autor:	Kaufman D; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; University of Montreal Medical School, Montreal, QC, Canada., Djinbachian R; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Taghiakbari M; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Popescu Crainic I; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; University of Montreal Medical School, Montreal, QC, Canada.; Department of Internal Medicine, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Haumesser C; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; University of Montreal Medical School, Montreal, QC, Canada., Abou Khalil M; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Sidani S; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Liu Chen Kiow J; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., Panzini B; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada., von Renteln D; Montreal University Hospital Research Center (CRCHUM), Departement of Gastroenterology, Montreal, QC, Canada.; Department of Gastroenterology, Montreal University Hospital Center (CHUM), Montreal, QC, Canada.
Jazyk:	angličtina
Zdroj:	Journal of the Canadian Association of Gastroenterology [J Can Assoc Gastroenterol] 2023 Dec 23; Vol. 7 (2), pp. 149-153. Date of Electronic Publication: 2023 Dec 23 (Print Publication: 2024).
DOI:	10.1093/jcag/gwad057
Abstrakt:	Background: The virtual scale endoscope (VSE) helps endoscopists measure colorectal polyp size more accurately compared to visual assessment (VA). However, previous studies were not adequately powered to evaluate the sizing of polyps at clinically relevant size thresholds and relative accuracy for size subgroups. Methods: We created 64 artificial polyps of varied sizes and Paris class morphology, randomly assigned 1:1 to be measured (383 total measurement datapoints with VSE and VA by 6 endoscopists blinded to true size) in a colon model. We added data from two previous trials (480 measurement datapoints). We evaluated for correct classification of polyps into size groups at 3 mm, 5 mm, 10 mm, and 20 mm size thresholds and the relative size measurement accuracy for diminutive polyps (≤5 mm), small polyps (5-9 mm), large polyps at 10-19 mm, and polyps (≥20). Results: VSE had significantly less size group misclassifications at the 5 mm, and 10 mm thresholds (28 percent vs. 45 percent, P = 0.0159 and 26 percent vs. 44 percent, P = 0.0135, respectively). For the 3 mm and 20 mm thresholds, VSE had lower misclassifications; however, this was not statistically significant (36 percent vs. 46 percent, P = 0.3853 and 38 percent vs. 41 percent, P = 0.2705, respectively). The relative size measurement accuracy was significantly higher for VSE compared to VA for all size subgroups (diminutive ( P < 0.01), small polyps ( P < 0.01), 10-19 mm ( P < 0.01), and ≥20 mm ( P < 0.01)). Conclusion: VSE outperforms VA in categorizing polyps into size groups at the clinically relevant size thresholds of 5 mm and 10 mm. Using VSE resulted in significantly higher relative measurement accuracy for all size subgroups. Competing Interests: D. R. has received consultant or speaker fees from Boston Scientific Inc., ERBE Elektromedizin GmbH, and Pendopharm. The other authors declare that they have no conflict of interest. (© The Author(s) 2023. Published by Oxford University Press on behalf of the Canadian Association of Gastroenterology.)
Databáze:	MEDLINE
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