Gastric Cancer: A Comprehensive Literature Review.

Autor:	Mithany RH; Laparoscopic Colorectal Surgery, Kingston Hospital NHS Foundation Trust, Kingston Upon Thames, GBR., Shahid MH; Surgery, Glangwili General Hospital, Carmarthen, GBR., Manasseh M; General Surgery, Torbay and South Devon NHS Foundation Trust, Torquay, GBR., Saeed MT; Internal Medicine, Prince Philip Hospital, Llanelli, GBR., Aslam S; General Surgery, Lahore General Hospital, Lahore, PAK., Mohamed MS; General Surgery, Hillingdon Hospital, Uxbridge, GBR., Daniel N; Medical Laboratory Science, Ain Shams University Specialized Hospital, Cairo, EGY.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Mar 10; Vol. 16 (3), pp. e55902. Date of Electronic Publication: 2024 Mar 10 (Print Publication: 2024).
DOI:	10.7759/cureus.55902
Abstrakt:	Gastric cancer stands as a significant global health concern, particularly prevalent in Eastern Asia, with high mortality rates urging urgent attention and research efforts. This article comprehensively explores the epidemiology, anatomy, risk factors, pathophysiology, clinical presentation, diagnosis, staging, treatment modalities, prevention strategies, and survival rates associated with gastric cancer. Notably, Helicobacter pylori infection, dietary choices, and intricate stomach anatomy play pivotal roles in disease development. Early detection, utilizing staging, grading, and genetic testing for personalized treatment approaches is emphasized. Treatment modalities encompass surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy. Prevention strategies involve lifestyle changes, screening, and genetic counseling. Survival rates vary by stage, highlighting the need for individualized care. In conclusion, a collaborative global effort is essential to address the impact of gastric cancer and improve outcomes. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Mithany et al.)
Databáze:	MEDLINE
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