Feline leptospirosis prevalence worldwide: A systematic review and meta-analysis of diagnostic approaches.

Autor:	Andityas M; Veterinary Science Program, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Veterinary Technology Study Program, Department of Bioresources Technology and Veterinary, Vocational College, Universitas Gadjah Mada, 55281, Indonesia., Nuraini DM; Veterinary Science Program, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Department of Animal Science, Faculty of Animal Science, Sebelas Maret University, Surakarta, 57126, Indonesia., Sota P; Tropical Disease Research Center, WHO Collaborating Center for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Khon Kaen University, Khon Kaen, 40002, Thailand., Loong SK; Tropical Infectious Diseases Research and Education Centre, Higher Institution Centre of Excellence, Universiti Malaya, Kuala Lumpur, 50603, Malaysia., Sripa B; Tropical Disease Research Center, WHO Collaborating Center for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Khon Kaen University, Khon Kaen, 40002, Thailand.; Department of Tropical Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand., Sukon P; Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand., Tangkawattana P; Department of Veterinary Anatomy, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand., Tangkawattana S; Tropical Disease Research Center, WHO Collaborating Center for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Khon Kaen University, Khon Kaen, 40002, Thailand.; Department of Veterinary Pathobiology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Jazyk:	angličtina
Zdroj:	Veterinary world [Vet World] 2024 Feb; Vol. 17 (2), pp. 255-272. Date of Electronic Publication: 2024 Feb 01.
DOI:	10.14202/vetworld.2024.255-272
Abstrakt:	Background and Aim: Leptospirosis in felids (domestic and wild cats) presents an ongoing challenge in our understanding. Numerous studies have reported the detection of Leptospira spp. in these feline populations, highlighting their potential as zoonotic carriers. This systematic review and meta-analysis aimed to provide insight into the global prevalence of leptospirosis in domestic and wild cats. Materials and Methods: We conducted extensive searches across five databases (PubMed, Scopus, Web of Science, Science Direct, and Google Scholar) following the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols guidelines. Random-effect meta-analyses were performed using R software version 4.3.0 to estimate pooled prevalence rates. Subgroup meta-analyses were conducted based on continents, diagnostic methods, sample types, and wildcat genera. Results: A total of 71 articles on leptospirosis in domestic cats and 23 articles on leptospirosis in wild cats met the eligibility criteria. Our findings indicated a significantly higher pooled seroprevalence of leptospirosis in domestic cats compared with infection prevalence (9.95% [95% confidence interval (CI), 7.60%-12.54%] vs. 4.62% [95% CI, 2.10%-7.83%], p = 0.01). In contrast, no significant difference was observed in pooled seroprevalence and infection prevalence among wild cats (13.38% [95% CI, 6.25%-21.93%] vs. 2.9% [95% CI, 0.00%-18.91%], p = 0.21). A subgroup meta-analysis of domestic cats revealed significant differences in seroprevalence across continents, sample types, and diagnostic methods. On the contrary, wild cats had no significant differences in any of the subgroups. Conclusion: Leptospira spp. have evidently been exposed to both domestic and wild cats, highlighting their potential roles as reservoir hosts for leptospirosis. These findings highlight the importance of considering felids as a possible public health threat. Competing Interests: The authors declare that they have no competing interests. (Copyright: © Andityas, et al.)
Databáze:	MEDLINE
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