Influence of idiopathic epilepsy on blood pressure and electrocardiography in dogs treated with phenobarbital.

Autor:	Trevisan YPA; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., de Freitas MS; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., de Freitas MN; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., Konrad J; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., Bortolini J; Department of Statistics of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., Schipiura AC; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., de Freitas AFB; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., Pazzini SS; Department of Clinical Pathology Laboratory at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., de Almeida ADBPF; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil., Sousa VRF; Department of Internal Medicine for Small Animals at the Veterinary Hospital of the Federal University of Mato Grosso. Av. Fernando Corrêa da Costa, nº 2367, Bairro Boa Esperança, Cuiabá, Mato Grosso, CEP: 78060-900, Brazil.
Jazyk:	angličtina
Zdroj:	Veterinary world [Vet World] 2024 Feb; Vol. 17 (2), pp. 356-360. Date of Electronic Publication: 2024 Feb 15.
DOI:	10.14202/vetworld.2024.356-360
Abstrakt:	Background and Aim: Dogs with idiopathic epilepsy (IE) experience a shortened lifespan, neurobehavioral changes, and an increased risk of comorbidities during the interictal period. There have been several reports of sudden death in humans with epilepsy, suggesting changes in cardiac rhythm secondary to seizures. In veterinary medicine, there are still no such conclusive studies. The present study aimed to evaluate blood pressure values, electrocardiographic findings, and laboratory parameters in dogs with IE treated with phenobarbital and to correlate these findings with possible cardiac alterations. Materials and Methods: Twenty-one dogs were divided into 11 healthy dogs and 10 idiopathic epileptic dogs for blood analysis, computerized electrocardiogram, and oscillometer-based blood pressure measurement. Results: QRS complex and S-T interval values differed significantly between groups, but blood pressure values were not significantly different. Conclusion: IE can occur with alterations in cardiac conduction and is a pathological condition. Competing Interests: The authors declare that they have no competing interests. (Copyright: © Trevisan, et al.)
Databáze:	MEDLINE
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