Expression of Calretinin Expression in Odontogenic Cysts and Odontogenic Tumors - Original Research.

Autor: Pabbaraju S; Department of Oral and Maxillofacial Surgery, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India., Boddeda KR; Department of Pedodontics and Preventive Dentistry, KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India., Sankurathree S; KIMS Dental College and Hospital, Amalapuram, Andhra Pradesh, India., Menon I; Department of Public Health Dentistry, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India., Rai NP; Faculty of Dentistry, MAHSA University, Malaysia., Nagella SP; Department of Pediatric Dentistry, Faculty of Dentistry, MAHSA University, Selangor, Malaysia.
Jazyk: angličtina
Zdroj: Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2024 Feb; Vol. 16 (Suppl 1), pp. S227-S229. Date of Electronic Publication: 2024 Feb 29.
DOI: 10.4103/jpbs.jpbs_469_23
Abstrakt: Aim: The present study was conducted for assessing variability in calretinin expression among odontogenic cysts as well as tumor cases.
Materials and Methods: Fifteen cases were included in the present research consisting of cases like - dentigerous cyst, odontogenic keratocyst, apical radicular cyst along with tumors like ameloblastoma, ameloblastic carcinoma, adenomatoid odontogenic tumor. Calretinin antibody was used for immunohistochemical staining. The amount of expression of this calretinin was statistically analyzed with the help of Chi-square test where P < 0.05 was considered noteworthy statistically.
Results: Most cases of ameloblastomas were highly positive for calretinin expression as compared to other cysts and tumors. Therefore, the correlation of this variation of expression of calretinin was statistically noteworthy ( P = 0.00).
Conclusion: In this study, we concluded that for ameloblastomas, calretinin can be a specific marker immunohistochemically and can help in identifying the amount of aggressive spread of various odontogenic tumors.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.)
Databáze: MEDLINE
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