Intraparotid plexiform neurofibroma: A rare diagnostic challenge.

Autor: Khan AA; Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India., Ahuja S; Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India., Zaheer S; Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Jazyk: angličtina
Zdroj: Diagnostic cytopathology [Diagn Cytopathol] 2024 Jul; Vol. 52 (7), pp. E164-E167. Date of Electronic Publication: 2024 Apr 10.
DOI: 10.1002/dc.25322
Abstrakt: Isolated intraparotid neurofibromas are exceptionally rare and often associated with neurofibromatosis type 1 (NF1). Diagnosing these tumors proves challenging because of the clinical resemblance to primary salivary gland masses. This case report details an 18-year-old with a painful, enlarging parotid mass, diagnosed through fine needle aspiration biopsy (FNAB) revealing myxoid stroma and spindle cells. Magnetic resonance imaging confirmed a plexiform neurofibroma involving the parotid gland and facial nerve. Histopathology validated the diagnosis, emphasizing the importance of cytological and radiological correlation. Notably, the absent NF1 association makes this case unique. Surgical excision with facial nerve reconstruction was performed, highlighting the complexity of managing such rare intraparotid neurofibromas. Awareness of this entity is crucial for accurate diagnosis and appropriate management.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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