Actinotignum schaalii infection: Challenges in diagnosis and treatment.

Autor:	Sahuquillo-Arce JM; Servicio de Microbiología, Hospital Doctor Moliner, Serra, Spain.; Grupo de Investigación de Infecciones Respiratorias, IIS La Fe, Valencia, Spain., Suárez-Urquiza P; Servicio de Microbiología, Hospital Universitari i Politècnic La Fe, Valencia, Spain., Hernández-Cabezas A; Servicio de Microbiología, Hospital Universitari i Politècnic La Fe, Valencia, Spain., Tofan L; Servicio de Análisis Clínicos, Hospital Universitari i Politècnic La Fe, Valencia, Spain., Chouman-Arcas R; Servicio de Microbiología, Hospital Francesc de Borja, Gandia, Spain., García-Hita M; Servicio de Microbiología, Hospital de la Vega Lorenzo Guirao, Cieza, Spain., Sabalza-Baztán O; Servicio de Microbiología, Hospital General Universitari de Castelló, Castellón de la Plana, Spain., Sellés-Sánchez A; Hospital General Universitario Santa Lucía, Cartagena, Spain., Lozano-Rodríguez N; Servicio de Microbiología, Hospital General Universitari de Castelló, Castellón de la Plana, Spain., Martí-Cuñat J; Servicio de Microbiología, Hospital Universitari i Politècnic La Fe, Valencia, Spain., López-Hontangas JL; Servicio de Microbiología, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
Jazyk:	angličtina
Zdroj:	Heliyon [Heliyon] 2024 Mar 22; Vol. 10 (7), pp. e28589. Date of Electronic Publication: 2024 Mar 22 (Print Publication: 2024).
DOI:	10.1016/j.heliyon.2024.e28589
Abstrakt:	Actinotignum schaalii affects elderly people and is associated with individuals with urological-related predispositions, but can be found in a variety of locations, such as cutaneous, intraabdominal, genitourinary and surgical infections. Disseminated infections occur less frequently and are by and large related to urinary tract colonisation. This pathogen is often neglected due to growth requirements, especially in urinary tract infections. We present 107 Actinotignum schaalii isolated from genitourinary samples (80.4%), from skin and soft tissue infections (13.1%), from bone and deep tissue infection (4.7%) and from blood cultures (1.9%). The automated system Alfred 60/AST was paramount for the isolation of 77.6% of the UTI. All the isolates tested were susceptible to penicillin, ampicillin, linezolid, vancomycin, teicoplanin, rifampicin and tetracycline. In conclusion, we present a large series of Actinotignum schaalii infections. This pathogen is hard to isolate, and is resistant to commonly used empirical antimicrobials. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2024 The Authors.)
Databáze:	MEDLINE
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