Autor: |
Bradfute SB; University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA., Calisher CH; Colorado State University, Fort Collins, Colorado, USA., Klempa B; Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia., Klingström J; Linköping University, Linköping, Sweden., Kuhn JH; Integrated Research Facility at Fort Detrick, Frederick, Maryland, USA., Laenen L; University Hospitals Leuven, Leuven, Belgium., Tischler ND; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, Chile.; Universidad San Sebastián, Santiago, Chile., Maes P; Zoonotic Infectious Diseases Unit, Rega Institute, KU Leuven, Leuven, Belgium. |
Abstrakt: |
Hantaviridae is a family for negative-sense RNA viruses with genomes of about 10.5-14.6 kb. These viruses are maintained in and/or transmitted by fish, reptiles, and mammals. Several orthohantaviruses can infect humans, causing mild, severe, and sometimes-fatal diseases. Hantavirids produce enveloped virions containing three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hantaviridae, which is available at ictv.global/report/hantaviridae. |