Cardiac Muscle Injury and Echocardiographic Plus Electrocardiographic Findings in Patients With 2019 Novel Coronavirus (COVID-19): A Retrospective Cohort Study.

Autor:	Abohelwa M; Cardiovascular Division, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA., Mohamed AA; School of Public Health, Imperial College London, London, United Kingdom., Del-Rio-Pertuz G; Cardiovascular Division, Department of Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Elgwairi E; Cardiovascular Division, Department of Internal Medicine, HCA Healthcare, Kansas City, Kansas, USA., Nguyen TH; Cardiovascular Division, Department of Internal Medicine, Texas Tech University Health Sciences Center at Lubbock, Lubbok, Texas, USA., Elmassry M; Cardiovascular Division, Department of Internal Medicine, Texas Tech University Health Sciences Center at Lubbock, Lubbok, Texas, USA., Parmar K; Department of Internal Medicine, Texas Tech University Health Sciences Center at Lubbock, Lubbock, Texas, USA., Rao S; Texas Tech University Health Science Center, School of Medicine, Lubbock, Texas, USA., Patel B; Texas Tech University Health Science Center, School of Medicine, Lubbock, Texas, USA., Hamous K; Department of Emergency Medicine, Baylor Scott and White University, Temple, Texas, USA., Mittal N; Department of Internal Medicine, University of Texas Health Sciences Center at Houston, Houston, Texas, USA., Sethi P; Cardiovascular Division, Department of Internal Medicine, Texas Tech University Health Sciences Center at Lubbock, Lubbok, Texas, USA., Nugent K; Department of Internal Medicine, Pulmonary/Critical Care Division, Texas Tech Health Sciences Center at Lubbock, Lubbock, Texas, USA., Shurmur S; Cardiovascular Division, Department of Internal Medicine, Texas Tech University Health Sciences Center at Lubbock, Lubbok, Texas, USA.
Jazyk:	angličtina
Zdroj:	CJC open [CJC Open] 2023 Oct 13; Vol. 6 (2Part A), pp. 108-117. Date of Electronic Publication: 2023 Oct 13 (Print Publication: 2024).
DOI:	10.1016/j.cjco.2023.10.005
Abstrakt:	Background: Myocardial injury has been described in coronavirus-2019 (COVID-19). Few studies have reported cardiovascular imaging data with transthoracic echocardiography (TTE) and electrocardiography (ECG) findings in COVID-19 patients, and their correlation with mortality. Methods: We conducted a retrospective cohort study that included COVID-19 patients from March 2020 through February 2021 who had TTE and ECG during hospital admission. Myocardial injury was defined by an elevated high-sensitivity troponin T level > 20 ng/L. Bivariate analysis was used to compare patients with myocardial injury and those without. Multivariate logistic regression analysis was performed to identify the variables associated with mortality. Results: A total of 438 patients were included. The mean age was 62.1 ± 14.9 years, and 58.9% were male. A total of 149 patients died, with a mortality rate of 34%. A total of 260 patients (59.4%) had myocardial injury. The average left ventricular ejection fraction was 59.8% ± 11.2%, with 30 patients (6.8%) having an ejection fraction of < 40%. Patients with myocardial injury had higher mortality than those without ( P < 0.05, χ 2 test). A multiple regression analysis model indicated that age, race and/or ethnicity, the development of acute respiratory distress syndrome, shock, the need for vasopressors, mechanical ventilation, and hemodialysis were the variables significantly associated with mortality. Conclusion: COVID-19 patients with myocardial injury had higher mortality than those without. Age, race and/or ethnicity, acute respiratory distress syndrome, shock, the need for vasopressors, mechanical ventilation, and hemodialysis were the clinical variables associated with mortality. The TEE and ECG variables studied were not significantly associated with mortality. (© 2023 The Authors.)
Databáze:	MEDLINE
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