Evaluating patient factors, operative management and postoperative outcomes in trauma laparotomy patients worldwide: a protocol for a global observational multicentre trauma study.

Autor:	Bath MF; International Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK mb2583@cam.ac.uk., Kohler K; International Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.; Department of Anaesthesia, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hobbs L; International Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.; Department of Anaesthesia, East and North Hertfordshire NHS Trust, Stevenage, UK., Smith BG; International Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK., Clark DJ; Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Kwizera A; Department of Anesthesia, Makerere University, Kampala, Uganda., Perkins Z; Centre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.; Major Trauma Service, Royal London Hospital, Barts Health NHS Trust, London, UK., Marsden M; Centre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.; Academic Department of Military Surgery and Trauma, Research and Clinical Innovation, Defence Medical Services, Birmingham, UK., Davenport R; Centre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK.; Major Trauma Service, Royal London Hospital, Barts Health NHS Trust, London, UK., Davies J; Cambridge Colorectal Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Amoako J; Department of Surgery, Korle Bu Teaching Hospital, Accra, Ghana.; University of Ghana Medical School, Accra, Ghana., Moonesinghe R; National Clinical Director for Critical and Perioperative Care, NHS England, London, UK., Weiser T; Department of Surgery, Stanford University, Palo Alto, California, USA., Leather AJM; School of Life Course and Population Sciences, King's College London, London, UK., Hardcastle T; Department of Surgical Sciences, Mandela School of Medicine (NRMSM), University of KwaZulu-Natal, Durban, South Africa.; Trauma and Burns Unit, Inkosi Albert Luthuli Central Hospital, KwaZulu-Natal Department of Health, Durban, South Africa., Naidoo R; Department of Surgery, Ngwelezana Hospital, Empangeni, South Africa., Nördin Y; Emergency Medical Care System (SAMU), Jalisco State, Mexico., Conway Morris A; Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK., Lakhoo K; Department of Paediatric Surgery, University of Oxford, Oxford, UK., Hutchinson PJ; Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; NIHR Global Health Research Group on Acquired Brain and Spine Injury, Cambridge, UK., Bashford T; International Health Systems Group, Department of Engineering, University of Cambridge, Cambridge, UK.; Department of Anaesthesia, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2024 Apr 05; Vol. 14 (4), pp. e083135. Date of Electronic Publication: 2024 Apr 05.
DOI:	10.1136/bmjopen-2023-083135
Abstrakt:	Introduction: Trauma contributes to the greatest loss of disability-adjusted life-years for adolescents and young adults worldwide. In the context of global abdominal trauma, the trauma laparotomy is the most commonly performed operation. Variation likely exists in how these patients are managed and their subsequent outcomes, yet very little global data on the topic currently exists. The objective of the GOAL-Trauma study is to evaluate both patient and injury factors for those undergoing trauma laparotomy, their clinical management and postoperative outcomes. Methods: We describe a planned prospective multicentre observational cohort study of patients undergoing trauma laparotomy. We will include patients of all ages who present to hospital with a blunt or penetrating injury and undergo a trauma laparotomy within 5 days of presentation to the treating centre. The study will collect system, patient, process and outcome data, following patients up until 30 days postoperatively (or until discharge or death, whichever is first). Our sample size calculation suggests we will need to recruit 552 patients from approximately 150 recruiting centres. Discussion: The GOAL-Trauma study will provide a global snapshot of the current management and outcomes for patients undergoing a trauma laparotomy. It will also provide insight into the variation seen in the time delays for receiving care, the disease and patient factors present, and patient outcomes. For current standards of trauma care to be improved worldwide, a greater understanding of the current state of trauma laparotomy care is paramount if appropriate interventions and targets are to be identified and implemented. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.)
Databáze:	MEDLINE
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