A machine-readable specification for genomics assays.

Autor:	Booeshaghi AS; Department of Bioengineering, University of California, Berkeley, CA, 94720, United States., Chen X; Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, 518055, China., Pachter L; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, United States.; Department of Computing and Mathematical Sciences, California Institute of Technology, Pasadena, CA, 91125, United States.
Jazyk:	angličtina
Zdroj:	Bioinformatics (Oxford, England) [Bioinformatics] 2024 Mar 29; Vol. 40 (4).
DOI:	10.1093/bioinformatics/btae168
Abstrakt:	Motivation: Understanding the structure of sequenced fragments from genomics libraries is essential for accurate read preprocessing. Currently, different assays and sequencing technologies require custom scripts and programs that do not leverage the common structure of sequence elements present in genomics libraries. Results: We present seqspec, a machine-readable specification for libraries produced by genomics assays that facilitates standardization of preprocessing and enables tracking and comparison of genomics assays. Availability and Implementation: The specification and associated seqspec command line tool is available at https://www.doi.org/10.5281/zenodo.10213865. (© The Author(s) 2024. Published by Oxford University Press.)
Databáze:	MEDLINE
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