The role of hydrogels in the management of brain tumours: a narrative review.

Autor:	Anas Z; Dow University of Health Sciences., Hasan SFS; Dow University of Health Sciences., Moiz MA; Dow University of Health Sciences., Zuberi MAW; Dow University of Health Sciences., Shah HH; Dow University of Health Sciences., Ejaz A; Dow University of Health Sciences., Dave T; Bukovinian State Medical University, Chernivtsi, Ukraine., Panjwani MH; Dow University of Health Sciences., Rauf SA; Liaquat National Medical College, Karachi, Pakistan., Hussain MS; Dow University of Health Sciences., Waseem R; Liaquat National Medical College, Karachi, Pakistan.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Feb 08; Vol. 86 (4), pp. 2004-2010. Date of Electronic Publication: 2024 Feb 08 (Print Publication: 2024).
DOI:	10.1097/MS9.0000000000001809
Abstrakt:	Conventional therapeutic techniques for brain tumours have limitations and side effects, necessitating the need for alternative treatment options. MRI-monitored therapeutic hydrogel systems show potential as a non-surgical approach for brain tumour treatment. Hydrogels have unique physical and chemical properties that make them promising for brain tumour treatment, including the ability to encapsulate therapeutic agents, provide sustained and controlled drug release, and overcome the blood-brain barrier for better penetration. By combining hydrogel systems with MRI techniques, it is possible to develop therapeutic approaches that provide real-time monitoring and controlled release of therapeutic agents. Surgical resection remains important, but there is a growing need for alternative approaches that can complement or replace traditional methods. The objective of this comprehensive narrative review is to evaluate the potential of MRI-monitored therapeutic hydrogel systems in non-surgical brain tumour treatment. Competing Interests: None declared by the authors.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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