[Estimation of prevalence of chronic Chagas disease in Brazilian municipalitiesEstimación de la prevalencia de la enfermedad de Chagas crónica en los municipios brasileños].

Autor:	Laporta GZ; Centro Universitário FMABC Santo AndréSP Brasil Centro Universitário FMABC, Santo André, SP, Brasil., Lima MM; Secretaria de Vigilância em Saúde e Ambiente Ministério da Saúde BrasíliaDF Brasil Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brasil., Maia da Costa V; Secretaria de Vigilância em Saúde e Ambiente Ministério da Saúde BrasíliaDF Brasil Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brasil., de Lima Neto MM; Secretaria de Vigilância em Saúde e Ambiente Ministério da Saúde BrasíliaDF Brasil Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brasil., Palmeira SL; Secretaria de Vigilância em Saúde e Ambiente Ministério da Saúde BrasíliaDF Brasil Secretaria de Vigilância em Saúde e Ambiente, Ministério da Saúde, Brasília, DF, Brasil., Rodovalho SR; Organização Pan-Americana da Saúde Organização Mundial da Saúde BrasíliaDF Brasil Organização Pan-Americana da Saúde/Organização Mundial da Saúde, Brasília, DF, Brasil., Aragón López MA; Organização Pan-Americana da Saúde Organização Mundial da Saúde BrasíliaDF Brasil Organização Pan-Americana da Saúde/Organização Mundial da Saúde, Brasília, DF, Brasil.
Jazyk:	portugalština
Zdroj:	Revista panamericana de salud publica = Pan American journal of public health [Rev Panam Salud Publica] 2024 Apr 04; Vol. 48, pp. e28. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
DOI:	10.26633/RPSP.2024.28
Abstrakt:	Objective: The objective of this study is to estimate the prevalence of chronic Chagas disease (CCD) in Brazil: in the general population, in women, and in women of childbearing age. Methods: A meta-analysis of the literature was conducted to extract data on the prevalence of CCD in municipalities in Brazil in the 2010-2022 period: in the general population, in women, and in women of childbearing age. Municipal-level CCD indicators available in health information systems were selected. Statistical modeling of the data extracted from the meta-analysis (based on data obtained from information systems) was applied to linear, generalized linear, and additive models. Results: The five most appropriate models were selected from a total of 549 models tested to obtain a consensus model (adjusted R 2 = 54%). The most important predictor was self-reported CCD in the primary health care information system. Zero prevalence was estimated in 1 792 (32%) of Brazil's 5 570 municipalities; in the remaining 3 778 municipalities, average prevalence of the disease was estimated at 3.25% (± 2.9%). The number of carriers of CCD was estimated for the Brazilian population (~3.7 million), for women (~2.1 million) and for women of childbearing age (~590 000). The disease reproduction rate was calculated at 1.0336. All estimates refer to the 2015-2016 period. Conclusions: The estimated prevalence of CCD, especially among women of childbearing age, highlights the challenge of vertical transmission in Brazilian municipalities. Mathematical projections suggest that these estimates should be included in the national program for the elimination of vertical transmission of Chagas disease.
Databáze:	MEDLINE
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