Ischemic Stroke as an Initial Manifestation of Antiphospholipid Syndrome in an Adolescent: A Case Report.

Autor: Gonzalez-Salido J; Medicine, Universidad La Salle, Mexico City, MEX., Barron-Cervantes NM; School of Medicine, Universidad Panamericana, Mexico City, MEX., Colado-Martinez J; School of Medicine, Universidad La Salle, Mexico City, MEX., Arechavala Lopez SF; Medicine, Universidad Autónoma Metropolitana, Mexico City, MEX., Mosqueda-Larrauri VL; School of Medicine, Universidad Nacional Autónoma de México, Mexico City, MEX., Ortiz-Herrera JL; School of Medicine, Universidad Nacional Autónoma de México, Mexico City, MEX., Piña-Rosales E; Internal Medicine, Fundación Clínica Médica Sur, Mexico City, MEX., Martinez-Bautista J; Neurology, Fundación Clínica Médica Sur, Mexico City, MEX.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Mar 05; Vol. 16 (3), pp. e55579. Date of Electronic Publication: 2024 Mar 05 (Print Publication: 2024).
DOI: 10.7759/cureus.55579
Abstrakt: Cerebrovascular diseases in pediatric patients are relatively rare. Ischemic stroke in adolescents is associated with a poor prognosis. The most common causes include systemic diseases, such as heart disease and hypercoagulation disorders. It is important to mention that one of the most common acquired hypercoagulation states is the antiphospholipid syndrome (APS). Patients with this disease may present stroke as the first clinical manifestation, which not only increases morbidity in these patients but presents a diagnostic challenge. This case presents one example of how APS can present as a pediatric stroke. The diagnostic approach should always be through the presence of specific antibodies accompanied by the presence of a thromboembolic episode proven by catheterization or an imaging study. In the brain, the preferred imaging study is magnetic resonance imaging. Management is based on anticoagulation therapy and continuous monitoring in the intensive care unit.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Gonzalez-Salido et al.)
Databáze: MEDLINE