Polidocanol-foam treatment of varicose veins: Quality-of-life impact compared to conventional surgery.

Autor: Sakugawa LS; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Portela FSO; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil. Electronic address: fsoaresportela@gmail.com., Louzada ACS; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Portugal MFC; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Teivelis MP; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, SP, Brazil., Mendes CA; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Pinheiro LL; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, SP, Brazil., Silva MFAD; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Fioranelli A; Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil., Wolosker N; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, SP, Brazil.
Jazyk: angličtina
Zdroj: Clinics (Sao Paulo, Brazil) [Clinics (Sao Paulo)] 2024 Apr 03; Vol. 79, pp. 100346. Date of Electronic Publication: 2024 Apr 03 (Print Publication: 2024).
DOI: 10.1016/j.clinsp.2024.100346
Abstrakt: Background and Objective: Lower limb varicose veins are a prevalent disease associated with several available treatment options, including conventional surgery and polidocanol foam sclerotherapy. However, few studies have analyzed therapeutic modality outcomes based on Patient-Reported Outcome Measures (PROMs). This large sample-size study was designed to evaluate the outcomes of polidocanol foam sclerotherapy compared to conventional surgery based on an analysis of PROMs.
Methods: This was a prospective, observational, and qualitative study of 205 patients who underwent varicose vein treatment with either polidocanol foam sclerotherapy (57 patients, 90 legs) or conventional surgery (148 patients, 236 legs). Patients were preoperatively assessed and re-evaluated 30 days after the procedure using the Venous Disease Severity Score (VCSS) and specific venous disease quality-of-life questionnaires (VEINES-QoL/Sym).
Results: Both treatments significantly improved VCSS and VEINES results 30 days after the procedure (p < 0.05). However, surgery promoted greater improvements in VCSS (on average 4.02-points improvement, p < 0.001), VEINES-QoL (average 8-points improvement, p < 0.001), and VEINES-Sym (average 11.66 points improvement, p < 0.001) than did sclerotherapy. Postoperative pain and aesthetic concerns about the legs were the domains of the questionnaires in which the results varied the most between the treatment modalities, with worse results for sclerotherapy.
Conclusion: Both polidocanol foam sclerotherapy and conventional surgery positively impact patients' quality of life after 30 days, but the improvement is more significant for patients who undergo conventional surgery.
Competing Interests: Conflicts of interest The authors declare no conflicts of interest.
(Copyright © 2024 HCFMUSP. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE