High-Dose Buprenorphine Initiation in the Management of Opioid Use Disorder in Pregnancy.
| Autor: | Berry M; Division of Maternal-Fetal Medicine and the Department of Psychiatry and Behavioral Health, The Ohio State University, Columbus, Ohio., Kiefer MK, Hinely KA, Bowden H, Jordan A, Vilensky M, Rood KM |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Obstetrics and gynecology [Obstet Gynecol] 2024 Jun 01; Vol. 143 (6), pp. 815-818. Date of Electronic Publication: 2024 Apr 04. |
| DOI: | 10.1097/AOG.0000000000005572 |
| Abstrakt: | Buprenorphine is commonly used as a treatment for opioid use disorder (OUD). Transition to buprenorphine traditionally has been done using a low-dose initiation regimen due to concerns surrounding precipitated withdrawal. There are increasing data supporting use of a high-dose initiation regimen in the nonpregnant population. This retrospective case series describes six individuals with OUD who underwent high-dose buprenorphine initiation in pregnancy. There were no instances of sedation, respiratory depression, supplemental oxygen use, or death. All individuals were successfully transitioned to buprenorphine. These findings provide support for high-dose buprenorphine initiation in pregnancy, but future large studies are needed. Competing Interests: Financial Disclosure The authors did not report any potential conflicts of interest. (Copyright © 2024 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|