Perifoveal exudative vascular anomalous complex (PEVAC) resembling lesion in a patient with multiple myeloma.

Autor:	Jadnanansing AI; Department of Ophthalmology, AZ Sint-Jan, Ruddershove 10, Bruges, Belgium., Martinez Ciriano JP; Medical Retina Service, Rotterdam Eye Hospital, Schiedamse Vest 180, Rotterdam, the Netherlands., van Droogenbroeck J; Department of Hematology, AZ Sint-Jan, Ruddershove 10, Bruges, Belgium., Spielberg L; Department of Ophthalmology, AZ Sint-Jan, Ruddershove 10, Bruges, Belgium., Vanhonsebrouck E; Department of Ophthalmology, AZ Sint-Jan, Ruddershove 10, Bruges, Belgium.
Jazyk:	angličtina
Zdroj:	American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2023 Jul 16; Vol. 34, pp. 101891. Date of Electronic Publication: 2023 Jul 16 (Print Publication: 2024).
DOI:	10.1016/j.ajoc.2023.101891
Abstrakt:	Purpose: To report a case of a perifoveal exudative vascular anomalous complex (PEVAC) resembling lesion in a patient with multiple myeloma. Observations: A 56-year-old male with multiple myeloma presented with sudden moderate vision loss in the right eye. Best-corrected visual acuity was 20/25 in his right eye. Fundus examination showed a vascular irregularity in the perifoveal region. Fluorescein angiography (FA) revealed an isolated perifoveal aneurysmal lesion with minimal leakage. On optical coherence tomography (OCT) examination, a large oval structure with a hyperreflective wall and exudation was visualised. Three weeks later, spontaneous improvement of the intraretinal fluid was observed on OCT without treatment. However, 3 months later the macular edema recurred. The appearance of the aneurysmal lesion is similar to a PEVAC lesion, which is an isolated well-defined perifoveal intraretinal vascular abnormality presenting on OCT as a round hyperreflective structure with a dark lumen containing variably reflective material and is commonly associated with cystic intraretinal fluid. Conclusions and Importance: PEVAC was originally described as occurring in healthy patients, but recent observations suggest that it also appears in association with other retinal/choroidal vascular abnormalities or underlying cardiovascular abnormalities. Our case supports this hypothesis by demonstrating a PEVAC resembling lesion in a patient with multiple myeloma. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 Published by Elsevier Inc.)
Databáze:	MEDLINE
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