Acute demyelinating encephalomyelitis in a child with pulmonary tuberculosis.

Autor:	Singh J; Departments of Pediatrics and Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India., Sharma P; Departments of Pediatrics and Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India., Randev S; Departments of Pediatrics and Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India., Kaur N; Departments of Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India., Kumar P; Departments of Pediatrics and Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India., Guglani V; Departments of Pediatrics and Radiodiagnosis, Government Medical College and Hospital, Chandigarh, India.
Jazyk:	angličtina
Zdroj:	Paediatrics and international child health [Paediatr Int Child Health] 2024 Aug; Vol. 44 (2), pp. 49-51. Date of Electronic Publication: 2024 Apr 03.
DOI:	10.1080/20469047.2024.2335422
Abstrakt:	Tuberculosis is a leading cause of mortality in children worldwide. One of the greatest challenges in its management is the difficulty of diagnosis as the manifestations are non-specific and often mimic other illnesses. Neurological infection occurs in approximately 1% of patients diagnosed with tuberculosis, and usually takes the form of tuberculous meningitis or tuberculoma. An 11-year-old girl who was diagnosed with acute disseminated encephalomyelitis, a rare immunological manifestation of tuberculosis, is presented. She recovered completely after a course of high-dose systemic corticosteroids in addition to anti-tuberculosis treatment. Considering the immense burden of this infectious disease, recognition and understanding of the uncommon manifestations are important to enable appropriate and timely treatment. Abbreviations: ADEM: acute disseminated encephalomyelitis; ATT: anti-tuberculosis therapy; CBNAAT: cartridge-based nucleic acid amplification test; CNS: central nervous system; CSF: cerebrospinal fluid; CT: computed tomography; FLAIR: fluid attenuated inversion recovery; IFN: interferon; MRI: magnetic resonance imaging; MTB: Mycobacterium tuberculosis ; TB: tuberculosis; TNF: tumour necrosis factor.
Databáze:	MEDLINE
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