Planar-chiral arene ruthenium complexes: synthesis, separation of enantiomers, and application for catalytic C-H activation.

Autor: Boym MA; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru.; National Research University Higher School of Economics, 7 Vavilova str., Moscow, 117312, Russia., Pototskiy RA; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru., Podyacheva ES; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru.; National Research University Higher School of Economics, 7 Vavilova str., Moscow, 117312, Russia., Chusov DA; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru.; National Research University Higher School of Economics, 7 Vavilova str., Moscow, 117312, Russia., Nelyubina YV; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru.; Moscow Institute of Physics and Technology, 9 Institutskiy per., Dolgoprudny, 141700, Russia., Perekalin DS; A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, 119334, Russia. dsp@ineos.ac.ru.; National Research University Higher School of Economics, 7 Vavilova str., Moscow, 117312, Russia.
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Apr 18; Vol. 60 (33), pp. 4491-4494. Date of Electronic Publication: 2024 Apr 18.
DOI: 10.1039/d4cc00181h
Abstrakt: Heating tert -butyl-tetraline with [( p -cymene)RuCl 2 ] 2 produces the racemic complex [(arene)RuCl 2 ] 2 , which can be separated into enantiomers by chromatography of its diastereomeric adducts with chiral phosphine ligand. The resolved chiral complex catalyzes C-H activation of N -methoxy-benzamides and their annulation with N -vinyl-pivaloyl amide giving dihydroisoquinolones in 50-80% yields and with 40-80% enantiomeric excess.
Databáze: MEDLINE
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