Identification of degenerated synaptic boutons in the dorsal claustrum of the cat after electrolytic lesions of the intralaminar thalamic nuclei.

Autor: Hinova-Palova D; Department of Anatomy, Histology and Embryology, Medical University of Sofia, Sofia, Bulgaria., Landzhov B; Department of Anatomy, Histology and Embryology, Medical University of Sofia, Sofia, Bulgaria., Edelstein L; Department of Experimental Neuroanatomy, Medimark Corporation, Del Mar, CA, USA., Fakih K; Department of Oral and Maxillofacial Surgery, Medical University of Sofia, Sofia, Bulgaria., Alexandrov A; Department of Forensic Medicine and Deontology, Medical University of Sofia, Sofia, Bulgaria., Kiriakova T; Department of Forensic Medicine and Deontology, Medical University of Sofia, Sofia, Bulgaria., Radeva E; Department of Conservative Dentistry, Faculty of Dental Medicine, Medical University Sofia, Sofia, Bulgaria., Gaydarski L; Department of Anatomy, Histology and Embryology, Medical University of Sofia, Sofia, Bulgaria., Denaro F; Department of Biology, Morgan State University, Baltimore, MD, USA., Paloff A; Department of Anatomy, Histology and Embryology, Medical University of Sofia, Sofia, Bulgaria.
Jazyk: angličtina
Zdroj: Journal of histotechnology [J Histotechnol] 2024 Sep; Vol. 47 (3), pp. 117-125. Date of Electronic Publication: 2024 Apr 02.
DOI: 10.1080/01478885.2024.2335827
Abstrakt: The aim of this study is to investigate whether the dorsal claustrum receives afferent input from the intralaminar thalamic nuclei - centromedian nucleus, central lateral nucleus and paracentral nucleus. The intralaminar thalamic nuclei of eight cats were electrolytically lesioned. We obtained samples from the dorsal claustrum for electron microscopic analysis from the second to the seventh post-procedural day. Two types of degenerated synaptic boutons were observed: electron-dense which formed the majority of boutons, and electron-lucent comprising the remaining samples. Between the second and seventh post-procedural day, we observed a steady increase in the number of electron-dense boutons which were diffusely distributed throughout the dorsal claustrum. Electron-dense degenerated boutons formed asymmetrical contacts with dendritic spines as well as with small and medium-sized dendrites. In contrast, electron-lucent degenerated boutons were observed in earlier post-procedural periods and formed symmetrical axodendritic contacts.
Databáze: MEDLINE
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