Pregnancy and the Autoimmune Patient.

Autor: Mills BS; University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX, 75390, USA., Bermas BL; University of Texas Southwestern Medical Center, 2001 Inwood Road, Dallas, TX, 75390, USA. Bonnie.Bermas@UTSouthwestern.edu.
Jazyk: angličtina
Zdroj: Current allergy and asthma reports [Curr Allergy Asthma Rep] 2024 May; Vol. 24 (5), pp. 261-267. Date of Electronic Publication: 2024 Apr 02.
DOI: 10.1007/s11882-024-01143-z
Abstrakt: Purpose of Review: This article will review the current understanding of the immunologic changes that occur during pregnancy. It will discuss the impact of pregnancy on the disease activity of autoimmune or inflammatory rheumatic diseases (AIRD). Lastly, it will highlight the most recent data on pre-conception and pregnancy management practices that can improve pregnancy outcomes in autoimmune patients.
Recent Findings: Pregnancy is an immunologically complex and dynamic state that may affect the activity of AIRDs, with more patients having active disease during pregnancy than previously thought. Uncontrolled inflammatory diseases are associated with poor pregnancy outcomes such as preeclampsia, small for gestational age infants, and prematurity. Pre-conception counseling and early pregnancy planning discussions can help ensure optimal disease control and medication management prior to attempting conception. Adequate control of AIRDs on pregnancy-compatible medications during the pre-conception, pregnancy, and postpartum periods is required for optimal pregnancy outcomes.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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