Recurrent inverse necrotizing infundibular crystalline folliculitis.

Autor: Ibraheim MK; Department of Dermatology, Loma Linda University, Loma Linda, California, USA., Storey L; Valley Skin Institute, Fresno, California, USA., North JP; Department of Dermatology and Pathology, University of California San Francisco, San Francisco, California, USA.
Jazyk: angličtina
Zdroj: Journal of cutaneous pathology [J Cutan Pathol] 2024 Jul; Vol. 51 (7), pp. 496-499. Date of Electronic Publication: 2024 Apr 02.
DOI: 10.1111/cup.14617
Abstrakt: Necrotizing infundibular crystalline folliculitis (NICF) is a rare type of necrotizing folliculitis. The disease typically manifests as folliculocentric papules arising in a seborrheic distribution. Only 23 cases exist in the literature. Most reported cases have arisen spontaneously, but a small number of drug-induced cases in the setting of epidermal-derived growth factor, vascular endothelial-derived growth factor, or PD-1 inhibitor therapy have been reported. Colonization by bacteria and/or yeast occurs frequently. The etiology remains unknown, but some suggest a complex interplay with an aberrant microbiome, sebaceous gland dysfunction, and perturbed EGFR signaling in follicular infundibula. Histopathologic findings include rupture of follicular epithelium, neutrophilic inflammation, and nodular cup-shaped crystal deposits. We present a case of spontaneous, recurrent NICF in an inverse pattern in the inguinal region.
(© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
Externí odkaz: