Association Between Young Adult Characteristics and Blood Pressure Trajectories.

Autor: An J; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA.; Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena CA USA., Fischer H; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA., Ni L; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA., Xia M; Division of General Medicine Columbia University Irving Medical Center New York NY USA., Choi SK; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA., Morrissette KL; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA., Wei R; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA., Reynolds K; Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USA.; Department of Health Systems Science Kaiser Permanente Bernard J. Tyson School of Medicine Pasadena CA USA., Muntner P; Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA., Safford MM; Division of General Internal Medicine Weill Cornell Medicine New York NY USA., Moran AE; Division of General Medicine Columbia University Irving Medical Center New York NY USA., Bellows BK; Division of General Medicine Columbia University Irving Medical Center New York NY USA., Isasi CR; Department of Epidemiology and Population Health Albert Einstein College of Medicine Bronx NY USA., Allen NB; Division of Epidemiology Northwestern University Chicago IL USA., Xanthakis V; Department of Medicine Boston University Chobanian and Avedisian School of Medicine Boston MA USA.; Department of Biostatistics Boston University School of Public Health Boston MA USA., Colantonio LD; Department of Epidemiology University of Alabama at Birmingham Birmingham AL USA., Zhang Y; Division of General Medicine Columbia University Irving Medical Center New York NY USA.
Jazyk: angličtina
Zdroj: Journal of the American Heart Association [J Am Heart Assoc] 2024 Apr 16; Vol. 13 (8), pp. e033053. Date of Electronic Publication: 2024 Apr 02.
DOI: 10.1161/JAHA.123.033053
Abstrakt: Background: Blood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP trajectories among a large diverse sample.
Methods and Results: We analyzed data from young adults, aged 18 to 39 years, with untreated BP <140/90 mm Hg at baseline from Kaiser Permanente Southern California (N=355 324). We used latent growth curve models to identify 10-year BP trajectories and to assess the associations between characteristics in young adulthood and BP trajectories. We identified the following 5 distinct systolic BP trajectories, which appeared to be determined mainly by the baseline BP with progressively higher BP at each year: group 1 (lowest BP trajectory, 7.9%), group 2 (26.5%), group 3 (33.0%), group 4 (25.4%), and group 5 (highest BP trajectory, 7.3%). Older age (adjusted odds ratio for 30-39 versus 18-29 years, 1.23 [95% CI, 1.18-1.28]), male sex (13.38 [95% CI, 12.80-13.99]), obesity (body mass index ≥30 versus 18.5-24.9 kg/m 2 , 14.81 [95% CI, 14.03-15.64]), overweight (body mass index 25-29.9 versus 18.5-24.9 kg/m 2 , 3.16 [95% CI, 3.00-3.33]), current smoking (1.58 [95% CI, 1.48-1.67]), prediabetes (1.21 [95% CI, 1.13-1.29]), diabetes (1.60 [95% CI, 1.41-1.81]) and high low-density lipoprotein cholesterol (≥160 versus <100 mg/dL, 1.52 [95% CI, 1.37-1.68]) were associated with the highest BP trajectory (group 5) compared with the reference group (group 2).
Conclusions: Traditional hypertension risk factors including smoking, diabetes, and elevated lipids were associated with BP trajectories in young adults, with obesity having the strongest association with the highest BP trajectory group.
Databáze: MEDLINE
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