Ameloblastic Carcinoma of the Maxilla With Uncommon Sinus Manifestations.

Autor: Khan F; Texas A&M School of Engineering Medicine, Houston, TX, USA., Somawardana I; Texas A&M School of Engineering Medicine, Houston, TX, USA., Mitchell M; Texas A&M School of Medicine, College Station, TX, USA., Adewumi MT; Department of Otolaryngology, Baylor Scott & White Medical Center, Temple, TX, USA., Berger B; Department of Pathology, Baylor Scott & White Medical Center, Temple, TX, USA., Marmie B; Department of Radiology, Baylor Scott & White Medical Center, Temple, TX, USA., Lopez L; Department of Pathology, Baylor Scott & White Medical Center, Temple, TX, USA., Clark D; Department of Otolaryngology, Baylor Scott & White Medical Center, Temple, TX, USA.
Jazyk: angličtina
Zdroj: Ear, nose, & throat journal [Ear Nose Throat J] 2024 Apr 01, pp. 1455613241245207. Date of Electronic Publication: 2024 Apr 01.
DOI: 10.1177/01455613241245207
Abstrakt: Ameloblastic carcinoma (AC) represents a distinct challenge in the realm of odontogenic malignancies due to its rarity and aggressive nature. We present a unique case of AC in a 70-year-old male, retired dry cleaner, with symptoms initially suggestive of chronic allergic rhinitis and recurrent acute sinusitis with asymmetric facial edema and paresthesia. Detailed evaluation revealed a prominent mass in the right maxillary sinus with extensive cortical destruction. Pathological assessment post-right maxillectomy identified a high-grade AC with malignant spindle cell transformation. The patient underwent subsequent interventions, including neck dissection and radiation therapy. Twelve months post-presentation, the patient was recovering appropriately without evidence of recurrence of malignancy. This case highlights the diagnostic challenges posed by AC as well as its unique presentations emphasizing the importance of a comprehensive approach and multidisciplinary management. It also raises considerations about potential chemical exposure implications in AC development.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE