Re-evaluating the relationship between youth with HIV and BMI in an age of increasing rates of overweight and obese youth.

Autor: Hill SV; University of Alabama at Birmingham, Birmingham, AL, USA. Samantha.hill.med@gmail.com., Hao J; University of Alabama at Birmingham, Birmingham, AL, USA., Newlin-Bradner M; Florida State University, Tallahassee, FL, USA., Long DM; University of Alabama at Birmingham, Birmingham, AL, USA., Budhwani H; Florida State University, Tallahassee, FL, USA., Simpson T; Tulane University, New Orleans, Louisiana, USA.
Jazyk: angličtina
Zdroj: BMC research notes [BMC Res Notes] 2024 Apr 01; Vol. 17 (1), pp. 97. Date of Electronic Publication: 2024 Apr 01.
DOI: 10.1186/s13104-024-06741-8
Abstrakt: Background: Newer antiretrivirals (ART) have shifted the metabolic experiences of people with HIV (PWH) from those of wasting syndrome to increases in body mass index (BMI). This study sought to examine the relationship between BMI and ART use among youth with HIV (YWH).
Methods: Charts from YWH ages 10-24 with at least two documented BMIs at least 6 months apart between 2017 and 2020 were included (N = 44). Statistical analyses were conducted in SAS 9.4.
Results: Clients were predominately African American (66%) males (73%) aged 19-24 years (64%), with men having sex with men (48%) being the most common mode of transmission. YWH on non-integrase inhibitor (INSTI) regimens had greater absolute increases in BMI compared to those on INSTI regimens (p = 0.03). Fourteen percent of clients using INSTI experienced an increase in BMI class from normal to overweight or overweight to obese; no non-INSTI users changed BMI class. Time since diagnosis and BMI change due to weight gain were positively associated (p = 0.03) among behaviorally-acquired YWH.
Conclusions: Increasing BMI and changing BMI classes may be more likely among YWH using INSTI. More longitudinal studies inclusive of diet and exercise profiles are needed to understand the relationship between INSTI and YWH BMI.
(© 2024. The Author(s).)
Databáze: MEDLINE
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