Spontaneous Tumor Lysis Syndrome Secondary to Metastatic Pancreatic Adenocarcinoma.

Autor: Gusdorf J; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Markovitz NH; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Ricketts C; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Ono Y; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Lam BD; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Berry J; Division of Hematology and Hematologic Malignancies, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Dockterman J; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Reddy S; Division of Gastroenterology, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Jazyk: angličtina
Zdroj: ACG case reports journal [ACG Case Rep J] 2024 Mar 28; Vol. 11 (4), pp. e01305. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).
DOI: 10.14309/crj.0000000000001305
Abstrakt: Spontaneous tumor lysis syndrome (STLS) secondary to metastatic pancreatic adenocarcinoma is a rare clinical phenomenon. An 86-year-old woman with a history of pancreatic cysts presented to the emergency department with progressive fatigue, transaminitis, elevated lactate dehydrogenase, and acute kidney injury of unclear etiology. Abdominal imaging and celiac lymph node biopsy were consistent with metastatic pancreatic adenocarcinoma. Her clinical status deteriorated requiring intensive care unit transfer, and her laboratory results were found to be consistent with STLS. Despite treatment, she entered multisystem organ failure and died shortly after. This case adds to the literature of STLS in pancreatic adenocarcinomas.
(© 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
Databáze: MEDLINE
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