Treatment With Voclosporin and Anifrolumab in a Patient With Lupus Nephritis and Refractory Discoid Lupus Erythematosus: A Case Report and Literature Review.

Autor: Karagenova R; Rheumatology, University of Hawaii John A. Burns School of Medicine, Honolulu, USA., Vodusek Z; Rheumatology, Johns Hopkins University School of Medicine, Baltimore, USA., Krimins R; Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, USA., Krieger A; Rheumatology, Johns Hopkins University School of Medicine, Baltimore, USA., Timlin H; Rheumatology, Johns Hopkins University School of Medicine, Baltimore, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Mar 01; Vol. 16 (3), pp. e55321. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
DOI: 10.7759/cureus.55321
Abstrakt: Systemic lupus erythematosus (SLE) is a complex heterogeneous disease with multiple clinical manifestations. Recently, two medications, anifrolumab and voclosporin, have been approved for the treatment of adults with SLE and lupus nephritis (LN), respectively. We present the case of an elderly woman with LN and refractory discoid lupus erythematosus (DLE), who was treated successfully with a combination of voclosporin and anifrolumab without major infections.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Karagenova et al.)
Databáze: MEDLINE